Results of the radiation dose of head, body and tail of hippocampus in nasopharyngeal carcinoma patients treated with intensity modulated radiotherapy.
Results of the radiation dose of head, body and tail of hippocampus in nasopharyngeal carcinoma patients treated with intensity modulated radiotherapy.
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鼻咽癌调强放疗患者海马头、体、尾部辐射剂量结果
DOI：
10.1038/s41598-018-23127-6
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发表时间：
2018-04-04
影响因子：
4.6
通讯作者：
Ming C
中科院分区：
文献类型：
--
作者：
Zong-Wen S;Lei S;Qinglin L;Yue K;Feng-Lei D;Tie-Ming X;Yong-Hong H;Qiao-Ying H;Xiao-Zhong C;Yuan-Yuan C;Ming C
本研究旨在分析调强放疗(IMRT)治疗鼻咽癌(NPC)患者头、体、尾海马区的照射剂量。采用韦氏成人智力量表中文修订版(WAIS-CR)评定患者的认知功能。将HC分为HC头部(HH)、HC体部(HB)和HC尾部(HT)，并对指标进行分析。分别于放疗前和放疗后3个月进行WAIS-CR测试。左、右侧HC平均辐射剂量分别为(1147 ± 976)cGy1011 ± 602 cGy.不同剂量HH、Hb、HT的辐射剂量和照射体积依次减小。5例患者放疗前、后正序评分分别为8.60 ± 1.34、8.0 ± 1.00(P = 0.43)，逆序评分分别为5.80 ± 0.84、5.20 ± 0.84(P = 0.07)。HH、Hb、Ht的辐射剂量不同，其中HH的辐射剂量最高，应特别重视。
This study is to analyze the radiation dose of head, body and tail of hippocampus (HC) of nasopharyngeal carcinoma (NPC) patients treated with intensity modulated radiotherapy (IMRT). Evaluate cognitive function of patients with Wechsler adult intelligence scale-Chinese revised (WAIS-CR). HC were segmented into HC head (HH), HC body (HB) and HC tail (HT) and the indexes were then analyzed. WAIS-CR was tested before and 3months after radiotherapy. The mean radiation dose of left and right HC was (1147 ± 976)cGy, (1011 ± 602)cGy respectively. The radiation dose and the volume exposed in different dose of HH, HB and HT decreased in turn. For 5 patients, before and after radiotherapy, the regular-order score was 8.60 ± 1.34, 8.0 ± 1.00 (P = 0.43), while the reverse-order score was 5.80 ± 0.84, 5.20 ± 0.84 (P = 0.07). The radiation dose of HH, HB and HT was different, and the radiation dose of HH was the highest, which should be emphasized especially.
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影响因子：
3.7
作者：
Han G;Liu D;Gan H;Denniston KA;Li S;Tan W;Hu D;Zhen W;Wang Z
通讯作者：
Wang Z
影响因子：
2.6
作者：
Ariza, Mar;Serra-Grabulosa, Josep M.;Sahuquillo, Juan
通讯作者：
Sahuquillo, Juan
影响因子：
5.7
作者：
Hackert, VH;den Heijer, T;Breteler, MMB
通讯作者：
Breteler, MMB
DOI：
10.1002/ar.21493
发表时间：
2012-01-01
影响因子：
2
作者：
Greene, Sarah J.;Killiany, Ronald J.
通讯作者：
Killiany, Ronald J.
影响因子：
11
作者：
SCOVILLE, WB;MILNER, B
通讯作者：
MILNER, B