Socio-Demographic Determinants Associated with Blastocystis Infection in Arequipa, Peru.

Socio-Demographic Determinants Associated with Blastocystis Infection in Arequipa, Peru.
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DOI:
10.4269/ajtmh.20-0631
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发表时间:
2020-11-16
期刊:
The American journal of tropical medicine and hygiene
影响因子:
--
通讯作者:
Castillo-Neyra R
Castillo-Neyra R
中科院分区:
其他
文献类型:
--
作者:
Salazar-Sánchez RS;Ascuña-Durand K;Ballón-Echegaray J;Vásquez-Huerta V;Martínez-Barrios E;Castillo-Neyra R

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芽囊原虫是人类肠道中最常见的原生动物之一,也是一种与不卫生的生活条件有关的人畜共患生物。该原虫分布广泛,病原学不明确,致病性不明确。在秘鲁,研究报告称许多地区都存在芽囊原虫,但据报告,阿雷基帕的发病率最高。本研究的目的是将芽囊原虫感染与健康的社会决定因素联系起来。我们招募并调查了232名感染和未感染的参与者,他们来自至少有一名囊胚感染者的房屋。所有标本均用生理盐水离心浓缩法浓缩,湿封片镜检,亚甲基染色粪便涂片证实。我们发现,在研究样本中,人类囊胚的患病率为51.3%。我们还发现了芽囊原虫感染与城市周边地区以及使用替代非饮用水供应之间的统计相关性,表明这些是人类芽囊原虫感染的危险因素。
Blastocystis is one of the most common protozoa in the human gut and a zoonotic organism related to unsanitary living conditions. This protozoon shows a broad distribution, unclear symptomatology, and undefined pathogenicity. In Peru, studies report the presence of Blastocystis in many regions, but the highest prevalence levels are reported in Arequipa. The aim of this study was to link Blastocystis infection with social determinants of health. We recruited and surveyed 232 infected and uninfected participants from houses with at least one Blastocystis-infected person. All samples were concentrated by spin concentration method in saline solution, examined by wet mount under light microscopy and confirmed with methylene-stained stool smear. We found a human Blastocystis prevalence of 51.3% in the study sample. We also found statistical associations between Blastocystis infection and peri-urban location in the city as well as the use of alternative non-domiciliary water supplies, suggesting these are risk factors for human Blastocystis infection.
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