Symptomatic SARS-CoV-2 Episodes and Health-Related Quality of Life.

Symptomatic SARS-CoV-2 Episodes and Health-Related Quality of Life.
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DOI:
10.1007/s40258-023-00810-y
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发表时间:
2023-09
影响因子:
3.6
通讯作者:
Petrou, Stavros
Petrou, Stavros
中科院分区:
医学3区
文献类型:
--
作者:
Alacevich, Caterina;Thalmann, Inna;Nicodemo, Catia;de Lusignan, Simon;Petrou, Stavros
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通过循证研究了解人口的身心健康需求是制定卫生政策的优先事项。在COVID-19大流行期间,人口福祉急剧下降。症状性疾病发作的经历与健康相关的生活质量之间的关系记录较少。这项研究分析了症状性COVID-19疾病与健康相关生活质量之间的关系。这些分析来自对2020年在英国进行的全国数字症状监测调查数据的横截面分析。我们使用症状和检测结果数据识别疾病发作,并分析了经验证的健康相关生活质量结局,包括健康效用评分(以0-1基数量表为索引)和EuroQoL EQ-5D-5L测量生成的视觉模拟量表(VAS)评分(0-100量表)。计量经济学模型控制了受访者的人口统计学和社会经济学特征、合并症、社会隔离措施以及区域和时间固定效应。结果显示,常见SARS-CoV-2症状的经历与EQ-5D-5L所有维度(活动性、自我护理、日常活动、疼痛/不适和焦虑/抑郁)的健康相关生活质量较差显著相关,效用评分下降-0.13,EQ-VAS评分下降-15。这些发现对敏感性分析和基于限制性测试结果的定义是稳健的。这项循证研究强调,在未来的大流行浪潮中,需要针对那些经历症状发作的人采取干预措施和服务,并有助于量化SARS-CoV-2治疗在健康相关生活质量方面的益处。在线版本包含补充材料,可通过10.1007/s40258-023-00810-y获得。
Understanding the physical and mental health needs of the population through evidence-based research is a priority for informing health policy. During the COVID-19 pandemic, population wellbeing dramatically dropped. The relationship between experiences of symptomatic illness episodes and health-related quality of life has been less documented. This study analysed the association between symptomatic COVID-19 illness and health-related quality of life. The analyses drew from a cross-sectional analysis of data from a national digital symptoms’ surveillance survey conducted in the UK in 2020. We identified illness episodes using symptoms and test results data and we analysed validated health-related quality of life outcomes including health utility scores (indexed on a 0–1 cardinal scale) and visual analogue scale (VAS) scores (0–100 scale) generated by the EuroQoL’s EQ-5D-5L measure. The econometric model controlled for respondents’ demographic and socioeconomic characteristics, comorbidities, social isolation measures, and regional and time fixed effects. The results showed that the experience of common SARS-CoV-2 symptoms was significantly associated with poorer health-related quality of life across all EQ-5D-5L dimensions of mobility, self-care, usual activities, pain/discomfort and anxiety/depression, a decrement in utility score of − 0.13 and a decrement in the EQ-VAS score of − 15. The findings were robust to sensitivity analyses and restrictive test results-based definitions. This evidence-based study highlights the need for targeting of interventions and services towards those experiencing symptomatic episodes during future waves of the pandemic and helps to quantify the benefits of SARS-CoV-2 treatment in terms of health-related quality of life. The online version contains supplementary material available at 10.1007/s40258-023-00810-y.
DOI: 10.1038/s41598-023-33642-w
发表时间: 2023-05-22
期刊: SCIENTIFIC REPORTS
影响因子: 4.6
作者:
Alacevich, Caterina;Thalmann, Inna;Nicodemo, Catia;de Lusignan, Simon;Petrou, Stavros
通讯作者: Petrou, Stavros
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DOI: 10.3390/ijerph18030847
发表时间: 2021-01-20
影响因子: --
作者:
Algahtani FD;Hassan SU;Alsaif B;Zrieq R
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DOI: 10.1371/journal.pone.0102634
发表时间: 2014-07-17
期刊: PLOS ONE
影响因子: 3.7
作者:
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通讯作者: Beutels, Philippe
DOI: 10.1136/bmj.316.7133.736
发表时间: 1998-03-07
影响因子: 105.7
作者:
Kind, P;Dolan, P;Williams, A
通讯作者: Williams, A
DOI: 10.1007/s11136-011-9903-x
发表时间: 2011-12
影响因子: 3.5
作者:
Herdman, M.;Gudex, C.;Lloyd, A.;Janssen, M. F.;Kind, P.;Parkin, D.;Bonsel, G.;Badia, X.
通讯作者: Badia, X.