Self-regulation of frontal-midline theta facilitates memory updating and mental set shifting.
Self-regulation of frontal-midline theta facilitates memory updating and mental set shifting.
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DOI：
10.3389/fnbeh.2014.00420
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发表时间：
2014
影响因子：
3
通讯作者：
Herrmann CS
中科院分区：
文献类型：
--
作者：
Enriquez-Geppert S;Huster RJ;Figge C;Herrmann CS
通过脑电图（EEG）测量的额中线（fm）θ振荡已被认为是执行功能的神经“工作语言”。当认知处理或任务表现增强时，它们的力量也会增加。因此，问题出现了学习增加fm-theta振幅是否会在功能上影响任务探测执行功能（EF）的行为表现。在这里，神经反馈（NF），一种学习方法，以自我上调fm-theta超过fm电极，对四个最具代表性的EF，记忆更新，设置移位，冲突监测，和电机抑制的影响。在开始之前和完成个性化的，八个会话间隙间隔NF干预后，三回，字母/数字任务切换，Stroop和停止信号任务进行了测试，同时测量EEG。自我决定的fm-theta上调及其对执行功能的假定作用与积极控制组（所谓的伪神经反馈组）进行了比较。训练后与任务相关的fm-theta活动在两组之间有显著差异。然而，更重要的是，在NF之后，观察到显著增强的行为表现。训练组在三背任务中表现出更高的准确性得分，在字母/数字任务切换中表现出更低的混合和转移成本。然而，这种特定的协议类型并没有影响性能的任务探测冲突监测和电机抑制。因此，我们的研究结果表明，认知控制的主动而非反应机制的调制。此外，与任务相关的EEG变化显示了NF和伪神经反馈组之间训练后的fm-theta的不同模式，这表明NF训练确实解决了EFs网络。总之，通过NF调节fm-theta可以作为执行功能障碍的有效治疗方法。
Frontal-midline (fm) theta oscillations as measured via the electroencephalogram (EEG) have been suggested as neural “working language” of executive functioning. Their power has been shown to increase when cognitive processing or task performance is enhanced. Thus, the question arises whether learning to increase fm-theta amplitudes would functionally impact the behavioral performance in tasks probing executive functions (EFs). Here, the effects of neurofeedback (NF), a learning method to self-up-regulate fm-theta over fm electrodes, on the four most representative EFs, memory updating, set shifting, conflict monitoring, and motor inhibition are presented. Before beginning and after completing an individualized, eight-session gap-spaced NF intervention, the three-back, letter/number task-switching, Stroop, and stop-signal tasks were tested while measuring the EEG. Self-determined up-regulation of fm-theta and its putative role for executive functioning were compared to an active control group, the so-called pseudo-neurofeedback group. Task-related fm-theta activity after training differed significantly between groups. More importantly, though, after NF significantly enhanced behavioral performance was observed. The training group showed higher accuracy scores in the three-back task and reduced mixing and shifting costs in letter/number task-switching. However, this specific protocol type did not affect performance in tasks probing conflict monitoring and motor inhibition. Thus, our results suggest a modulation of proactive but not reactive mechanisms of cognitive control. Furthermore, task-related EEG changes show a distinct pattern for fm-theta after training between the NF and the pseudo-neurofeedback group, which indicates that NF training indeed tackles EFs-networks. In sum, the modulation of fm-theta via NF may serve as potent treatment approach for executive dysfunctions.
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影响因子：
16.2
作者：
Buzsáki G;Logothetis N;Singer W
通讯作者：
Singer W
影响因子：
3
作者：
Arns, Martijn;Conners, C. Keith;Kraemer, Helena C.
通讯作者：
Kraemer, Helena C.
影响因子：
4.7
作者：
Donkers FC;Schwikert SR;Evans AM;Cleary KM;Perkins DO;Belger A
通讯作者：
Belger A
影响因子：
4.7
作者：
Clarke, AR;Barry, RJ;Selikowitz, M
通讯作者：
Selikowitz, M
影响因子：
4.7
作者：
Egner, T;Gruzelier, JH
通讯作者：
Gruzelier, JH