In the Age of Viral Pandemic, Can Ingredients Inspired by Human Milk and Infant Nutrition Be Repurposed to Support the Immune System?

In the Age of Viral Pandemic, Can Ingredients Inspired by Human Milk and Infant Nutrition Be Repurposed to Support the Immune System?
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DOI:
10.3390/nu13030870
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发表时间:
2021-03-06
期刊:
影响因子:
5.9
通讯作者:
Shah N
Shah N
中科院分区:
医学2区
文献类型:
--
作者:
Brink LR;Chichlowski M;Pastor N;Thimmasandra Narayanappa A;Shah N

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2020年,随着一场大流行病的到来,全球生活的各个方面都受到影响,人们对支持免疫系统的营养解决方案重新产生了兴趣。婴儿很容易受到感染,母乳喂养已被证明可以提供保护。因此,人乳是功能性营养成分来源的一个很好的模型,它可能在预防病毒性疾病方面发挥直接作用。本综述旨在总结有关母乳(乳铁蛋白、乳脂球膜、骨桥蛋白、单月桂酸甘油酯和母乳低聚糖)和婴儿营养(多不饱和脂肪酸、益生菌和益生菌)启发成分的文献,以支持对抗病毒感染和更广泛的免疫系统。我们相信,这些成分的应用可以跨越所有生命阶段,因此适用于儿科和成人营养。我们强调在这一领域进一步研究的机会,以帮助提供切实的营养解决方案,以支持一个人的免疫系统和对抗感染。
In 2020, with the advent of a pandemic touching all aspects of global life, there is a renewed interest in nutrition solutions to support the immune system. Infants are vulnerable to infection and breastfeeding has been demonstrated to provide protection. As such, human milk is a great model for sources of functional nutrition ingredients, which may play direct roles in protection against viral diseases. This review aims to summarize the literature around human milk (lactoferrin, milk fat globule membrane, osteopontin, glycerol monolaurate and human milk oligosaccharides) and infant nutrition (polyunsaturated fatty acids, probiotics and postbiotics) inspired ingredients for support against viral infections and the immune system more broadly. We believe that the application of these ingredients can span across all life stages and thus apply to both pediatric and adult nutrition. We highlight the opportunities for further research in this field to help provide tangible nutrition solutions to support one’s immune system and fight against infections.
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