Gyri-precise head model of transcranial direct current stimulation: improved spatial focality using a ring electrode versus conventional rectangular pad.
Gyri-precise head model of transcranial direct current stimulation: improved spatial focality using a ring electrode versus conventional rectangular pad.
复制标题
DOI：
10.1016/j.brs.2009.03.005
复制
发表时间：
2009-10
影响因子：
7.7
通讯作者：
Bikson, Marom
中科院分区：
文献类型：
--
作者：
Datta, Abhishek;Bansal, Varun;Diaz, Julian;Patel, Jinal;Reato, Davide;Bikson, Marom
传统的经颅直流电刺激（tDCS）的空间分辨率被认为是相对扩散，由于颅骨分散。然而，在这里，我们表明，电场可能会聚集在不同的脑回/脑沟网站由于组织结构/导电性的细节，特别是脑脊液（CSF）。我们使用高空间分辨率（1 mm 3）MRI衍生的有限元人体头部模型计算了tDCS期间诱导的皮质电场/电流密度大小;皮质脑回/脑沟得到解决。比较了常规矩形电极（7 × 5cm ~ 2）和环形电极（4 × 1）的空间聚焦性。矩形垫配置导致扩散（非焦点）调制，电场幅度最大值的离散集群。未在焊盘正下方观察到峰值感应电场幅度，而是在中间波瓣处观察到。4 × 1环导致增强的空间聚焦性，在激活电极正下方的沟和相邻脑回处具有峰值感应电场强度。皮质结构可以使用环配置进行局部靶向。解剖学上准确的高分辨率MRI为基础的前向模型可以指导“合理的”临床设计和优化的tDCS。
The spatial resolution of conventional transcranial direct current stimulation (tDCS) is considered to be relatively diffuse owing to skull dispersion. However, here we show that electric fields may be clustered at distinct gyri/sulci sites due to details in tissue architecture/conductivity notably cerebrospinal fluid (CSF). We calculated the cortical electric field/current density magnitude induced during tDCS using a high spatial resolution (1 mm3) MRI-derived finite element human head model; cortical gyri/sulci were resolved. The spatial focality of conventional rectangular-pad (7 × 5 cm2) and the ring (4 × 1) electrode configurations were compared. The rectangular-pad configuration resulted in diffuse (un-focal) modulation, with discrete clusters of electric field magnitude maxima. Peak induced electric field magnitude was not observed directly underneath the pads, but at an intermediate lobe. The 4 × 1 ring resulted in enhanced spatial focality, with peak induced electric field magnitude at the sulcus and adjacent gyri directly underneath the active electrode. Cortical structures may be focally targeted using ring configurations. Anatomically accurate high resolution MRI-based forward-models may guide the ‘rational’ clinical design and optimization of tDCS.
登录
查看更多内容
影响因子：
2.7
作者：
Akhtari, M;Bryant, HC;Sutherling, WW
通讯作者：
Sutherling, WW
影响因子：
4.4
作者：
Boggio, Paulo S.;Ferrucci, Roberta;Fregni, Felipe
通讯作者：
Fregni, Felipe
影响因子：
11
作者：
Boggio, P. S.;Khoury, L. P.;Fregni, F.
通讯作者：
Fregni, F.
DOI：
10.1097/yct.0b013e318183c6a4
发表时间：
2009-06
期刊：
The journal of ECT
影响因子：
--
作者：
Borckardt JJ;Linder KJ;Ricci R;Li X;Anderson B;Arana A;Nahas Z;Amassian V;Long J;George MS;Sackeim HA
通讯作者：
Sackeim HA
影响因子：
5.7
作者：
De Lucia, M.;Parker, G. J. M.;Walsh, V.
通讯作者：
Walsh, V.