Mosquito hemocyte-mediated immune responses.
Mosquito hemocyte-mediated immune responses.
复制标题
DOI：
10.1016/j.cois.2014.07.002
复制
发表时间：
2014-09-01
影响因子：
5.3
通讯作者：
Strand, Michael R.
中科院分区：
文献类型：
--
作者：
Hillyer, Julian F.;Strand, Michael R.
血细胞是蚊子免疫系统的关键组成部分，通过吞噬、溶解和黑化途径杀死病原体。单个蚊子含有500至4，000个血细胞，分为三个群体，即粒细胞，卵细胞和原血细胞。血细胞也可以通过它们的解剖位置来划分，其中75%的血细胞在血腔中循环（循环血细胞），25%的血细胞自身附着于组织（固着血细胞）。成年蚊子中超过85%的血细胞是粒细胞，其主要通过吞噬作用或溶解作用杀死病原体。另一方面，类酒细胞是黑化所需酶的主要生产者，而原血细胞是参与吞噬作用的小细胞。循环血细胞和固着血细胞都参与防御病原体。蚊子的循环系统也与血细胞相互作用，并促进消除进入血腔的潜在病原体。
Hemocytes are a key component of the mosquito immune system that kill pathogens via phagocytic, lytic and melanization pathways. Individual mosquitoes contain between 500 and 4,000 hemocytes, which are divided into three populations named granulocytes, oenocytoids and prohemocytes. Hemocytes can also be divided by their anatomical location with 75% of hemocytes circulating in the hemocoel (circulating hemocytes) and 25% of hemocytes attaching themselves to tissues (sessile hemocytes). Greater than 85% of the hemocytes in adult mosquitoes are granulocytes, which primarily kill pathogens by phagocytosis or lysis. Oenocytoids, on the other hand, are the major producers of the enzymes required for melanization while prohemocytes are small cells that participate in phagocytosis. Both circulating and sessile hemocytes engage in defense against pathogens. The circulatory system of mosquitoes also interacts with hemocytes and facilitates elimination of potential pathogens that enter the hemocoel.
登录
查看更多内容
影响因子：
9.8
作者：
Dong, Yuemei;Taylor, Harry E;Dimopoulos, George
通讯作者：
Dimopoulos, George
影响因子：
1.3
作者：
CHRISTENSEN, BM;HUFF, BM;CHRISTENSEN, LA
通讯作者：
CHRISTENSEN, LA
影响因子：
4.4
作者：
Aliota, Matthew T;Fuchs, Jeremy F;Mayhew, George F;Chen, Cheng-Chen;Christensen, Bruce M
通讯作者：
Christensen, Bruce M
影响因子：
2.8
作者：
Bryant, William B.;Michel, Kristin
通讯作者：
Michel, Kristin
影响因子：
4.4
作者：
Baton LA;Robertson A;Warr E;Strand MR;Dimopoulos G
通讯作者：
Dimopoulos G