Old and new models for the study of human ageing.

Old and new models for the study of human ageing.
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DOI:
10.1038/s41580-020-0266-4
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发表时间:
2020-09
期刊:
Nature reviews. Molecular cell biology
影响因子:
--
通讯作者:
Brunet A
Brunet A
中科院分区:
其他
文献类型:
--
作者:
Brunet A

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人的衰老与疾病的易感性有关。衰老的某些方面可以直接在人类身上进行研究,研究表明,衰老受到许多因素的影响,包括遗传、生活方式、性别和社会经济地位。但是,确定导致和调节衰老过程的因素往往需要实验干预和建模,而这些干预和建模只能在模型系统中进行。
Human ageing is associated with high susceptibility to disease. Some aspects of ageing can be studied directly in humans and have revealed that ageing is influenced by many factors, including genetics, lifestyle, sex and socio-economic status. But identifying the factors that cause and modulate the ageing process often requires experimental interventions and modelling that can only be performed in model systems.
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