A genomic catalog of Earth's microbiomes.
A genomic catalog of Earth's microbiomes.
复制标题
DOI:
10.1038/s41587-020-0718-6
复制
发表时间:
2021-04
影响因子:
46.9
通讯作者:
Eloe-Fadrosh EA
中科院分区:
文献类型:
--
作者:
Nayfach S;Roux S;Seshadri R;Udwary D;Varghese N;Schulz F;Wu D;Paez-Espino D;Chen IM;Huntemann M;Palaniappan K;Ladau J;Mukherjee S;Reddy TBK;Nielsen T;Kirton E;Faria JP;Edirisinghe JN;Henry CS;Jungbluth SP;Chivian D;Dehal P;Wood-Charlson EM;Arkin AP;Tringe SG;Visel A;IMG/M Data Consortium;Woyke T;Mouncey NJ;Ivanova NN;Kyrpides NC;Eloe-Fadrosh EA
The reconstruction of bacterial and archaeal genomes from shotgun metagenomes has enabled insights into the ecology and evolution of environmental and host-associated microbiomes. Here we applied this approach to >10,000 metagenomes collected from diverse habitats covering all of Earth’s continents and oceans, including metagenomes from human and animal hosts, engineered environments, and natural and agricultural soils, to capture extant microbial, metabolic and functional potential. This comprehensive catalog includes 52,515 metagenome-assembled genomes representing 12,556 novel candidate species-level operational taxonomic units spanning 135 phyla. The catalog expands the known phylogenetic diversity of bacteria and archaea by 44% and is broadly available for streamlined comparative analyses, interactive exploration, metabolic modeling and bulk download. We demonstrate the utility of this collection for understanding secondary-metabolite biosynthetic potential and for resolving thousands of new host linkages to uncultivated viruses. This resource underscores the value of genome-centric approaches for revealing genomic properties of uncultivated microorganisms that affect ecosystem processes. Cataloging microbial genomes from Earth’s environments expands the known phylogenetic diversity of bacteria and archaea.
登录
查看更多内容
影响因子:
3
作者:
Edgar RC
通讯作者:
Edgar RC
影响因子:
14.9
作者:
Chen IA;Chu K;Palaniappan K;Pillay M;Ratner A;Huang J;Huntemann M;Varghese N;White JR;Seshadri R;Smirnova T;Kirton E;Jungbluth SP;Woyke T;Eloe-Fadrosh EA;Ivanova NN;Kyrpides NC
通讯作者:
Kyrpides NC
影响因子:
14.9
作者:
Kalvari I;Argasinska J;Quinones-Olvera N;Nawrocki EP;Rivas E;Eddy SR;Bateman A;Finn RD;Petrov AI
通讯作者:
Petrov AI
影响因子:
16.6
作者:
Hua, Zheng-Shuang;Wang, Yu-Lin;Li, Wen-Jun
通讯作者:
Li, Wen-Jun
DOI:
10.1073/pnas.1402564111
发表时间:
2014-04-01
影响因子:
11.1
作者:
Howe, Adina Chuang;Jansson, Janet K.;Brown, C. Titus
通讯作者:
Brown, C. Titus