Precision Functional Mapping of the Subcortex and Cerebellum.

Precision Functional Mapping of the Subcortex and Cerebellum.
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DOI:
10.1016/j.cobeha.2020.12.011
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发表时间:
2021-08
影响因子:
5
通讯作者:
Greene DJ
Greene DJ
中科院分区:
心理学2区
文献类型:
--
作者:
Marek S;Greene DJ

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使用精确的功能图可以可靠地描述人类大脑功能网络在个体中的特征。这种方法需要从每个单独的受试者收集大量的功能磁共振成像(FMRI)数据。使用大脑皮质精确功能图谱的研究发现,个体在之前的群体平均方法描述的中心趋势周围,表现出独特的大脑功能网络表征。我们最近将精确功能图扩展到皮质下和小脑,揭示了这些结构中的几个新的组织原理。在这里,我们详细介绍这些原则,并提供关于皮质下结构和小脑的精确功能映射如何在临床上可翻译的见解。
Human functional brain networks can be reliably characterized within individuals using precision functional mapping. This approach entails the collection of large quantities of functional magnetic resonance imaging (fMRI) data from each individual subject. Studies employing precision functional mapping in the cerebral cortex have found that individuals manifest unique representations of functional brain networks around a central tendency described by previous group average approaches. We recently extended precision functional mapping to the subcortex and cerebellum, which has revealed several novel organizational principles within these structures. Here, we detail these principles and provide insights into how precision functional mapping of subcortical structures and the cerebellum may become clinically translatable.
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