Language prediction mechanisms in human auditory cortex.
Language prediction mechanisms in human auditory cortex.
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DOI：
10.1038/s41467-020-19010-6
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发表时间：
2020-10-16
影响因子：
16.6
通讯作者：
Tandon N
中科院分区：
文献类型：
--
作者：
Forseth KJ;Hickok G;Rollo PS;Tandon N
口语，无论是感知还是产生，都被认为是由一系列预测机制促进的。我们在37例患者的颅内记录使用深度探头植入沿着前后范围的颞上平面在节奏听，语音感知，语音生产。这些结果揭示了早期听觉皮层具有不同解剖和功能特征的两种预测机制。第一，本地化的双边Heschl的脑回和索引的低频相位，预测的声学事件的时间。第二个，本地化到颞平面仅在语言主导的皮层和高伽玛功率索引，显示了一个短暂的响应，在语音生产过程中被唯一抑制的声学刺激。计时刺激Heschl's gyrus选择性地干扰言语知觉，而刺激颞平面选择性地干扰言语产生。这项工作阐明了基本的声学基础设施，包括建筑和功能，为口语，接地认知模型的语音感知和生产在人类神经生物学。人类大脑在感知和生产过程中流畅地解析连续语音。使用直接的大脑记录加上刺激，作者确定了两个不同的预测机制，“什么时候”在Heschl的脑回和“什么”在颞平面的可分离的基板。
Spoken language, both perception and production, is thought to be facilitated by an ensemble of predictive mechanisms. We obtain intracranial recordings in 37 patients using depth probes implanted along the anteroposterior extent of the supratemporal plane during rhythm listening, speech perception, and speech production. These reveal two predictive mechanisms in early auditory cortex with distinct anatomical and functional characteristics. The first, localized to bilateral Heschl’s gyri and indexed by low-frequency phase, predicts the timing of acoustic events. The second, localized to planum temporale only in language-dominant cortex and indexed by high-gamma power, shows a transient response to acoustic stimuli that is uniquely suppressed during speech production. Chronometric stimulation of Heschl’s gyrus selectively disrupts speech perception, while stimulation of planum temporale selectively disrupts speech production. This work illuminates the fundamental acoustic infrastructure—both architecture and function—for spoken language, grounding cognitive models of speech perception and production in human neurobiology. The human brain fluently parses continuous speech during perception and production. Using direct brain recordings coupled with stimulation, the authors identify separable substrates underlying two distinct predictive mechanisms of “when” in Heschl’s gyrus and “what” in planum temporale.
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影响因子：
25
作者：
通讯作者：
--
影响因子：
3.8
作者：
Ghitza O
通讯作者：
Ghitza O
细胞外田地和电流的起源-EEG，ECOG，LFP和尖峰。
DOI：
10.1038/nrn3241
发表时间：
2012-05-18
期刊：
Nature reviews. Neuroscience
影响因子：
--
作者：
Buzsáki G;Anastassiou CA;Koch C
通讯作者：
Koch C
影响因子：
1.7
作者：
Bruns, A;Eckhorn, R;Ebner, A
通讯作者：
Ebner, A
影响因子：
5.7
作者：
Dale, AM;Fischl, B;Sereno, MI
通讯作者：
Sereno, MI