Iridocorneal angle imaging of a human donor eye by spectral-domain optical coherence tomography.

Iridocorneal angle imaging of a human donor eye by spectral-domain optical coherence tomography.
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DOI:
10.1038/s41598-023-37248-0
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发表时间:
2023-08-24
期刊:
影响因子:
4.6
通讯作者:
Juhasz, Tibor
Juhasz, Tibor
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Luo, Shangbang;Holland, Guy;Khazaeinezhad, Reza;Bradford, Samantha;Joshi, Rohan;Juhasz, Tibor

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Iridocorneal angle (ICA) details particularly the trabecular meshwork (TM), Schlemm’s canal (SC), and collector channels (CCs) play crucial roles in the regulation of the aqueous outflow in the eyes and are closely associated with glaucoma. Current clinical gonioscopy imaging provides no depth information, and studies of 3D high-resolution optical coherence tomography (OCT) imaging of these structures are limited. We developed a custom-built spectral-domain (SD-) OCT imaging system to fully characterize the angle details. Imaging of a human cadaver eye reveals the visibility of details in the TM/SC/CC region via a ’crossline’ scanning and a series of image processing. This shows that ICA imaging can be used for preoperative glaucoma inspections in the clinical setting with the proposed prototype.
使用扫频源光学相干断层扫描测量年龄对人类施莱姆氏管和小梁网形态的影响
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