Multiple recent horizontal transfers of a large genomic region in cheese making fungi.
Multiple recent horizontal transfers of a large genomic region in cheese making fungi.
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DOI：
10.1038/ncomms3876
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发表时间：
2014
影响因子：
16.6
通讯作者：
Brygoo, Yves
中科院分区：
文献类型：
--
作者：
Cheeseman, Kevin;Ropars, Jeanne;Renault, Pierre;Dupont, Joelle;Gouzy, Jerome;Branca, Antoine;Abraham, Anne-Laure;Ceppi, Maurizio;Conseiller, Emmanuel;Debuchy, Robert;Malagnac, Fabienne;Goarin, Anne;Silar, Philippe;Lacoste, Sandrine;Sallet, Erika;Bensimon, Aaron;Giraud, Tatiana;Brygoo, Yves
虽然原核生物中水平转移的程度和影响已得到广泛认可，但它们对真核王国的重要性尚不清楚，许多人认为这只是轶事。在这里，我们报告了最近在青霉菌属之间的巨大基因组岛的多次转移。存在于食品环境中。对奶酪制作中使用的两种主要丝状真菌 P. roqueforti 和 P. Cammberti 进行测序，并与青霉素生产者 P. rubens 进行比较，发现 P. roqueforti 中存在一个 575 kb 长的基因组岛（称为 Wallaby），在 P. Cammberti 和 P. rubens 的非同源基因座上以相同片段的形式存在。袋鼠仅在来自食品环境的青霉属菌株中检测到。小袋鼠包含大约 250 个预测基因，其中一些可能与微生物竞争有关。最近在食品环境中发生的多次真核转移为真核生物中这种未被充分研究且可能被低估的现象的重要性提供了有力的证据。 已知水平基因转移在原核生物进化中发挥重要作用，但其在真核生物中的影响和普遍性尚不清楚。在这里，作者对奶酪制作真菌 P. roqueforti 和 P. Cammberti 的基因组进行了测序，并为近期大型基因组区域的水平转移提供了证据。
While the extent and impact of horizontal transfers in prokaryotes are widely acknowledged, their importance to the eukaryotic kingdom is unclear and thought by many to be anecdotal. Here we report multiple recent transfers of a huge genomic island between Penicillium spp. found in the food environment. Sequencing of the two leading filamentous fungi used in cheese making, P. roqueforti and P. camemberti, and comparison with the penicillin producer P. rubens reveals a 575 kb long genomic island in P. roqueforti—called Wallaby—present as identical fragments at non-homologous loci in P. camemberti and P. rubens. Wallaby is detected in Penicillium collections exclusively in strains from food environments. Wallaby encompasses about 250 predicted genes, some of which are probably involved in competition with microorganisms. The occurrence of multiple recent eukaryotic transfers in the food environment provides strong evidence for the importance of this understudied and probably underestimated phenomenon in eukaryotes. Horizontal gene transfers are known to play an important role in prokaryote evolution but their impact and prevalence in eukaryotes is less clear. Here, the authors sequence the genomes of cheese making fungi P. roqueforti and P. camemberti, and provide evidence for recent horizontal transfers of a large genomic region.
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影响因子：
3.1
作者：
Hegedues, Nikoletta;Sigl, Claudia;Zadra, Ivo;Pocsi, Istvan;Marx, Florentine
通讯作者：
Marx, Florentine
影响因子：
56.9
作者：
Hotopp, Julie C. Dunning;Clark, Michael E.;Werren, John H.
通讯作者：
Werren, John H.
影响因子：
30.8
作者：
Friesen, Timothy L.;Stukenbrock, Eva H.;Oliver, Richard P.
通讯作者：
Oliver, Richard P.
DOI：
10.1016/j.ijfoodmicro.2009.11.014
发表时间：
2010-02-28
影响因子：
5.4
作者：
Giraud, Frederic;Giraud, Tatiana;Dupont, Joelle
通讯作者：
Dupont, Joelle
影响因子：
3
作者：
Hane, James K.;Oliver, Richard P.
通讯作者：
Oliver, Richard P.