Biomechanical evaluation of Ti-Nb-Sn alloy implants with a low Young's modulus.
Biomechanical evaluation of Ti-Nb-Sn alloy implants with a low Young's modulus.
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具有低模量的Ti-NB-SN合金植入物的生物力学评估。
DOI：
10.3390/ijms16035779
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发表时间：
2015-03-12
影响因子：
5.6
通讯作者：
Sasaki K
中科院分区：
文献类型：
--
作者：
Takahashi K;Shiraishi N;Ishiko-Uzuka R;Anada T;Suzuki O;Masumoto H;Sasaki K
种植牙被广泛使用，是一种可预测的治疗各种无牙病例。咬合负荷可能与种植体骨丢失和整合丧失有因果关系。使用与骨组织结合的机械生物学植入物可以减少应力集中。本研究的目的是研究钛-铌-锡合金作为种植体材料的生物力学行为、生物相容性和生物活性。并与cpTi进行比较。测定细胞增殖和碱性磷酸酶（ALP）活性。为了评估骨整合程度，进行了推入试验。在所有实验中，Ti-Nb-Sn合金和cpTi在制备表面上生长的细胞增殖和ALP活性相似。对比Ti-Nb-Sn合金种植体与cpTi种植体的推入测试值，两者无显著性差异。这些结果表明，用Ti-Nb-Sn制备的种植体具有与cpTi相似的生物学潜力，并且具有良好的骨整合能力。
Dental implants are widely used and are a predictable treatment in various edentulous cases. Occlusal overload may be causally related to implant bone loss and a loss of integration. Stress concentrations may be diminished using a mechanobiologically integrated implant with bone tissue. The purpose of this study was to investigate the biomechanical behavior, biocompatibility and bioactivity of a Ti-Nb-Sn alloy as a dental implant material. It was compared with cpTi. Cell proliferation and alkaline phosphatase (ALP) activity were quantified. To assess the degree of osseointegration, a push-in test was carried out. Cell proliferation and ALP activity in the cells grown on prepared surfaces were similar for the Ti-Nb-Sn alloy and for cpTi in all the experiments. A comparison between the Ti-Nb-Sn alloy implant and the cpTi implant revealed that no significant difference was apparent for the push-in test values. These results suggest that implants fabricated using Ti-Nb-Sn have a similar biological potential as cpTi and are capable of excellent osseointegration.
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影响因子：
7.6
作者：
Ogawa, T.;Saruwatari, L.;Ohno, N.
通讯作者：
Ohno, N.
影响因子：
3.1
作者：
Niinomi M;Nakai M
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影响因子：
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作者：
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DOI：
10.1016/j.msea.2006.01.131
发表时间：
2006-12-25
影响因子：
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作者：
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通讯作者：
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影响因子：
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作者：
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