Improving Cognitive Function with Nutritional Supplements in Aging: A Comprehensive Narrative Review of Clinical Studies Investigating the Effects of Vitamins, Minerals, Antioxidants, and Other Dietary Supplements.
Improving Cognitive Function with Nutritional Supplements in Aging: A Comprehensive Narrative Review of Clinical Studies Investigating the Effects of Vitamins, Minerals, Antioxidants, and Other Dietary Supplements.
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《衰老过程中营养补充剂对认知功能的改善：对研究维生素、矿物质、抗氧化剂及其他膳食补充剂效果的临床研究的综合叙述性综述》
DOI：
10.3390/nu15245116
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发表时间：
2023-12-15
期刊：
影响因子：
5.9
通讯作者：
Varga JT
中科院分区：
文献类型：
--
作者：
Fekete M;Lehoczki A;Tarantini S;Fazekas-Pongor V;Csípő T;Csizmadia Z;Varga JT
认知障碍和痴呆是日益严重的公共卫生问题，特别是考虑到全球人口预期寿命的不断延长。这些病症不仅影响个人及其家庭的生活质量，还对医疗保健系统造成重大经济负担。在此背景下，我们全面的叙述性综述批判性地审视了营养补充剂在缓解认知衰退方面的作用。在人们对用于增强认知的非药物干预措施兴趣日益浓厚的情况下，本综述深入探讨了维生素、矿物质、抗氧化剂和其他膳食补充剂的功效。通过对随机对照试验、观察性研究和荟萃分析进行系统评估，本综述聚焦于记忆增强、注意力改善、执行功能支持和神经保护等结果。研究结果表明，营养补充与认知健康之间存在复杂的相互作用，一些补充剂显示出有希望的结果，而其他补充剂则效果有限或取决于具体情况。综述强调了剂量、生物利用度以及个体对补充剂反应的差异的重要性。此外，它还涉及安全问题以及与常规治疗的潜在相互作用。通过清晰地概述当前的科学知识，本综述旨在指导医疗保健专业人员和研究人员就营养补充剂用于认知健康做出明智的决策。
Cognitive impairment and dementia are burgeoning public health concerns, especially given the increasing longevity of the global population. These conditions not only affect the quality of life of individuals and their families, but also pose significant economic burdens on healthcare systems. In this context, our comprehensive narrative review critically examines the role of nutritional supplements in mitigating cognitive decline. Amidst growing interest in non-pharmacological interventions for cognitive enhancement, this review delves into the efficacy of vitamins, minerals, antioxidants, and other dietary supplements. Through a systematic evaluation of randomized controlled trials, observational studies, and meta-analysis, this review focuses on outcomes such as memory enhancement, attention improvement, executive function support, and neuroprotection. The findings suggest a complex interplay between nutritional supplementation and cognitive health, with some supplements showing promising results and others displaying limited or context-dependent effectiveness. The review highlights the importance of dosage, bioavailability, and individual differences in response to supplementation. Additionally, it addresses safety concerns and potential interactions with conventional treatments. By providing a clear overview of current scientific knowledge, this review aims to guide healthcare professionals and researchers in making informed decisions about the use of nutritional supplements for cognitive health.
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DOI：
10.1093/gerona/glab104
发表时间：
2021-11-15
期刊：
The journals of gerontology. Series A, Biological sciences and medical sciences
影响因子：
--
作者：
Dorhout BG;Doets EL;van Dongen EJI;de Groot LCPGM;Haveman-Nies A
通讯作者：
Haveman-Nies A
DOI：
10.3390/ijerph191811549
发表时间：
2022-09-14
影响因子：
--
作者：
Csizmadia, Zoltan;Acs, Pongrac;Szollosi, Gergo Jozsef;Toth, Blanka;Kerti, Maria;Kovacs, Antal;Varga, Janos Tamas
通讯作者：
Varga, Janos Tamas
影响因子：
5.6
作者：
Balázs N;Bereczki D;Ajtay A;Oberfrank F;Kovács T
通讯作者：
Kovács T
DOI：
10.3390/ijerph18031360
发表时间：
2021-02-02
影响因子：
--
作者：
Suliburska J;Chmurzynska A;Kocylowski R;Skrypnik K;Radziejewska A;Baralkiewicz D
通讯作者：
Baralkiewicz D
影响因子：
5.6
作者：
Syed, Muslim Abbas;Aiyegbusi, Olalekan Lee;Marston, Eliot;Lord, Janet M.;Teare, Harriet;Calvert, Melanie
通讯作者：
Calvert, Melanie