Influence of suckling on gonadotropin secretion in the female rhesus monkey (Macaca mulatta).

Influence of suckling on gonadotropin secretion in the female rhesus monkey (Macaca mulatta).
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哺乳对雌性恒河猴(Macaca mulatta)促性腺激素分泌的影响。

DOI:
10.1095/biolreprod23.4.760
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发表时间:
1980
影响因子:
3.6
通讯作者:
Knobil,E
Knobil,E
中科院分区:
生物学2区
文献类型:
--
作者:
Plant,TM;Schallenberger,E;Hess,DL;McCormack,JT;Dufy-Barbe,L;Knobil,E

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外源性雌激素引起促性腺激素激增的能力在产后雌性恒河猴哺乳其婴儿,在产后女性的婴儿在出生时断奶,并在孕前女性担任这些断奶婴儿的养母,大约每月一次。雌激素对促性腺激素分泌的刺激作用被取消或严重抑制的前6个月的自然和寄养母亲的护理。相反,产后女性,其婴儿在出生时断奶,雌激素的管理,引起黄体生成素(LH)和卵泡刺激素(FSH)激增的第一次试验30天后交付。哺乳期妇女雌激素正反馈作用的消除与基础血清促性腺激素水平的抑制有关。这些结果表明,泌乳期雌性恒河猴促性腺激素分泌的长期抑制是由哺乳期婴儿的存在所引起的,并且与妊娠和分娩相关的前期事件无关。
The ability of exogenous estrogen to elicit gonadotropin surges was determined at approximately monthly intervals in postpartum female rhesus monkeys nursing their infants, in postpartum females whose infants were weaned at birth, and in pregestational females that served as foster mothers to these weaned infants. The stimulatory action of estrogen on gonadotropin secretion was abolished or severely inhibited for the first 6 months of nursing in both natural and foster mothers. In contrast, the administration of estrogen to postpartum females, whose infants were weaned at birth, elicited luteinizing hormone (LH) and follicle stimulating hormone (FSH) surges on the first trial 30 days after delivery. The abolition of the positive feedback action of estrogen in nursing mothers was associated with a suppression of basal serum gonadotropin levels. These findings demonstrate that the protracted inhibition of gonadotropin secretion in lactating female rhesus monkeys is occasioned by the presence of a suckling infant and is independent of antecedent events associated with gestation and parturition.
催乳素抑制猴子哺乳期间黄体生成素的释放
DOI: 10.1038/262507a0
发表时间: 1976
期刊: Nature
影响因子: 64.8
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DOI: 10.1111/j.1365-2265.1975.tb03300.x
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哺乳期和非哺乳期妇女产后期 LH/FSH 释放激素 (LRH) 对促性腺激素基础分泌与血浆雌二醇、孕酮和催乳素水平的影响。
DOI: 10.1530/acta.0.0840713
发表时间: 1977
期刊: Acta endocrinologica
影响因子: --
作者:
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DOI: 10.1210/jcem-49-3-422
发表时间: 1979
期刊: The Journal of clinical endocrinology and metabolism
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