Correlates of cortisol in human hair: implications for epidemiologic studies on health effects of chronic stress.
Correlates of cortisol in human hair: implications for epidemiologic studies on health effects of chronic stress.
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DOI：
10.1016/j.annepidem.2013.09.006
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发表时间：
2013-12
影响因子：
5.6
通讯作者：
Williams, Michelle A.
中科院分区：
文献类型：
--
作者：
Wosu, Adaeze C.;Valdimarsdottir, Unnur;Shields, Alexandra E.;Williams, David R.;Williams, Michelle A.
评估头发中的皮质醇浓度是测量长期皮质醇暴露的最新创新之一。我们对人类头发中皮质醇的相关性进行了系统回顾，为未来流行病学研究的设计、分析和解释提供信息。通过使用关键词“皮质醇”、“头发”、“混杂因素”、“慢性”、“压力”和“相关因素”在 PubMed、WorldCat 和 Web of Science 上进行电子搜索，确定了相关出版物。本次综述纳入了 39 项研究。尽管数据稀缺且存在一些不一致之处，但研究人员发现头发皮质醇浓度与压力相关的精神症状和疾病（例如创伤后应激障碍）、表明下丘脑-垂体-肾上腺轴慢性激活的医疗状况（例如库欣综合征）以及与慢性压力风险升高相关的其他生活状况（例如轮班工作）有关。一些研究的结果表明，体力活动、肥胖和药物滥用可能与头发皮质醇浓度相关。与短期皮质醇释放（唾液、血液和尿液）的测量相比，吸烟和使用口服避孕药似乎与头发皮质醇浓度无关。对孕妇的研究表明，在连续三个月内，头发皮质醇浓度会增加。头发皮质醇的研究为评估流行病学研究中皮质醇浓度的慢性变化提供了独特的机会。
Assessment of cortisol concentrations in hair is one of the latest innovations for measuring long-term cortisol exposure. We performed a systematic review of correlates of cortisol in human hair to inform the design, analysis and interpretation of future epidemiologic studies. Relevant publications were identified through electronic searches on PubMed, WorldCat, and Web of Science using keywords, “cortisol” “hair” “confounders” “chronic” “stress” and “correlates.” Thirty-nine studies were included in this review. Notwithstanding scarce data and some inconsistencies, investigators have found hair cortisol concentrations to be associated with stress-related psychiatric symptoms and disorders (e.g., PTSD), medical conditions indicating chronic activation of the hypothalamic-pituitary-adrenal axis (e.g., Cushing´s syndrome) and other life situations associated with elevated risk of chronic stress (e.g., shiftwork). Results from some studies suggest that physical activity, adiposity, and substance abuse may be correlates of hair cortisol concentrations. In contrast to measures of short-term cortisol release (saliva, blood, and urine), cigarette smoking and use of oral contraceptives appear to not be associated with hair cortisol concentrations. Studies of pregnant women indicate increased hair cortisol concentrations across successive trimesters. The study of hair cortisol presents a unique opportunity to assess chronic alterations in cortisol concentrations in epidemiologic studies.
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影响因子：
2.1
作者：
Cirimele, V;Kintz, P;Ludes, B
通讯作者：
Ludes, B
DOI：
10.1016/s0378-4347(00)00085-2
发表时间：
2000-04-14
期刊：
JOURNAL OF CHROMATOGRAPHY B
影响因子：
--
作者：
Bévalot, F;Gaillard, Y;Pépin, G
通讯作者：
Pépin, G
影响因子：
2.9
作者：
D'Anna-Hernandez, Kimberly L.;Ross, Randal G.;Laudenslager, Mark L.
通讯作者：
Laudenslager, Mark L.
影响因子：
4.7
作者：
Earle, TL;Linden, W;Wenberg, J
通讯作者：
Wenberg, J
影响因子：
5.8
作者：
Dekker, M. J. H. J.;Koper, J. W.;Tiemeier, H.
通讯作者：
Tiemeier, H.