Single-use thermoplastic microfluidic burst valves enabling on-chip reagent storage.
Single-use thermoplastic microfluidic burst valves enabling on-chip reagent storage.
复制标题
一次性热塑性微流体突发阀可实现片固剂的储存。
DOI:
10.1007/s10404-014-1494-8
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发表时间:
2015-05-01
影响因子:
2.8
通讯作者:
DeVoe, Don L.
中科院分区:
文献类型:
--
作者:
Rahmanian, Omid D.;DeVoe, Don L.
关键词:
A simple and reliable method for fabricating single-use normally closed burst valves in thermoplastic microfluidic devices is presented, using a process flow that is readily integrated into established workflows for the fabrication of thermoplastic microfluidics. An experimental study of valve performance reveals the relationships between valve geometry and burst pressure. The technology is demonstrated in a device employing multiple valves engineered to actuate at different inlet pressures that can be generated using integrated screw pumps. On-chip storage and reconstitution of fluorescein salt sealed within defined reagent chambers are demonstrated. By taking advantage of the low gas and water permeability of cyclic olefin copolymer, the robust burst valves allow on-chip hermetic storage of reagents, making the technology well suited for the development of integrated and disposable assays for use at the point of care.
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影响因子:
6.1
作者:
Rahmanian O;DeVoe DL
通讯作者:
DeVoe DL
影响因子:
6.1
作者:
van Oordt, Thomas;Barb, Yannick;von Stetten, Felix
通讯作者:
von Stetten, Felix
影响因子:
6.1
作者:
Garcia-Cordero, Jose L.;Kurzbuch, Dirk;Ricco, Antonio J.
通讯作者:
Ricco, Antonio J.
DOI:
10.1021/la302704t
发表时间:
2012-09-04
期刊:
Langmuir : the ACS journal of surfaces and colloids
影响因子:
--
作者:
Rahmanian O;Chen CF;DeVoe DL
通讯作者:
DeVoe DL
影响因子:
6.1
作者:
Chen, Guofang;Svec, Frantisek;Knapp, Daniel R.
通讯作者:
Knapp, Daniel R.