Mechanisms of chylomicron uptake into lacteals.

Mechanisms of chylomicron uptake into lacteals.
复制标题

DOI:
10.1111/j.1749-6632.2010.05716.x
复制
发表时间:
2010-10
影响因子:
5.2
通讯作者:
Dixon JB
Dixon JB
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Dixon JB

文献摘要

参考文献

被引文献

相似文献

从出生开始,营养素就在饮食功能中起着至关重要的作用。从新生儿富含脂质的饮食中吸收的大部分脂质通过淋巴系统进入血液循环,该淋巴系统将称为乳糜微粒的装载有脂质的颗粒从小肠的绒毛运输到心脏附近的静脉循环。鉴于这一作用的重要性,以及从肠道转运脂质是淋巴管系统最早发现的功能之一的事实,令人惊讶的是,关于乳糜微粒最初如何进入淋巴管的知之甚少。本次审查将侧重于被认为在这一进程中很重要的现有机制,并突出强调今后需要回答的重要问题。
Right from birth, the lymphatics play a crucial role in dietary functions. A majority of the lipid absorbed from the newborn’s lipid-rich diet enters the blood circulation through the lymphatic system, which transports triglyceride-loaded particles known as chylomicrons from the villi of the small intestine to the venous circulation near the heart. In light of the significance of this role, as well as the fact that lipid transport from the gut was one of the earliest discovered functions of the lymphatic vasculature, it is surprising that so little is known about how chylomicrons initially gain access to the lymphatic vessel. This review will focus on the current mechanisms thought to be important in this process and highlight important questions that need to be answered in the future.
DOI: 10.1016/j.devcel.2009.06.017
发表时间: 2009-08
期刊: DEVELOPMENTAL CELL
影响因子: 11.8
作者:
Bazigou, Eleni;Xie, Sherry;Chen, Chun;Weston, Anne;Miura, Naoyuki;Sorokin, Lydia;Adams, Ralf;Muro, Andres F.;Sheppard, Dean;Makinen, Taija
通讯作者: Makinen, Taija
DOI: 10.1006/mvre.2002.2428
发表时间: 2002-09-01
影响因子: 3.1
作者:
Azzali, G;Vitale, M;Arcari, ML
通讯作者: Arcari, ML
DOI: 10.1111/j.1749-6632.1964.tb52547.x
发表时间: 1964-01-01
期刊: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES-SERIES
影响因子: --
作者:
CASLEYSMITH, JR
通讯作者: CASLEYSMITH, JR
DOI: 10.1117/1.2135791
发表时间: 2005-11-01
影响因子: 3.5
作者:
Dixon, JB;Zawieja, DC;Coté, GL
通讯作者: Coté, GL
DOI: 10.1007/s10439-006-9225-2
发表时间: 2007-03-01
影响因子: 3.8
作者:
Dixon, J. Brandon;Gashev, Anatoliy A.;Cote, Gerard L.
通讯作者: Cote, Gerard L.