Coumarin-based fluorescent probe for the rapid detection of peroxynitrite 'AND' biological thiols.
Coumarin-based fluorescent probe for the rapid detection of peroxynitrite 'AND' biological thiols.
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基于香豆素的荧光探针，用于快速检测过氧亚硝酸盐和生物硫醇
作者：
基于香豆素的新型“AND”逻辑荧光探针 ROS-AHC 已开发用于同时检测 ONOO− 和生物硫醇。 ROS-AHC 在添加单一 GSH 或 ONOO− 分析物后仅表现出非常小的荧光响应。然而，暴露于两种分析物都会导致荧光显着增强。基于香豆素的新型“AND”逻辑荧光探针 ROS-AHC 已开发用于同时检测 ONOO− 和生物硫醇。
A coumarin-based novel ‘AND’ logic fluorescent probe ROS-AHC has been developed for the simultaneous detection of ONOO− and biological thiols. ROS-AHC was shown to exhibit only a very small fluorescence response upon addition of a single GSH or ONOO− analyte. Exposure to both analytes, however, resulted in a significant fluorescence enhancement. A coumarin-based novel ‘AND’ logic fluorescent probe ROS-AHC has been developed for the simultaneous detection of ONOO− and biological thiols.
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