Childhood abuse and adult-onset asthma among Peruvian women.
Childhood abuse and adult-onset asthma among Peruvian women.
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DOI：
10.1080/02770903.2017.1339243
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发表时间：
2018-04
期刊：
影响因子：
--
通讯作者：
Williams MA
中科院分区：
文献类型：
--
作者：
Banerjee D;Gelaye B;Zhong QY;Sanchez SE;Williams MA
已发现儿童期虐待与成年期发作的哮喘有关;然而，在低收入和中等收入国家，这种联系尚未得到研究，这些国家的性别暴力负担很高，包括儿童期虐待。我们研究了秘鲁孕妇在18岁或18岁以上被诊断出哮喘的几率与身体和性虐待史的关系。这项横断面研究收集了3081名孕妇的人口统计学特征、滥用史和哮喘诊断。Logistic回归程序估计了与滥用相关的哮喘诊断的校正比值比和95%置信区间（aOR，[95%CI]）。总体而言，71%的女性报告有滥用史（<18年），2.6%的队列参与者被诊断为哮喘。儿童期单纯身体虐待、单纯性虐待以及身体和性虐待的发生率分别为38%、8%和24%。仅身体虐待史（1.16，[0.63-2.17]）、仅性虐待史（2.11，[0.92-4.84]）或儿童期身体虐待和性虐待史（1.75，[0.94-3.29]）与哮喘发病率增加呈正相关，尽管在多变量分析中，相关性无统计学意义。然而，哮喘的几率随着滥用事件数量的增加而增加（ptrend=0.01）。报告≥3起滥用事件的女性发生哮喘的几率增加（1.88，[1.06-3.34]）。我们的研究结果并没有提供令人信服的证据表明，儿童虐待与秘鲁孕妇哮喘有关，但是，我们能够证明，越来越多的虐待事件与哮喘有关。需要进一步的研究来更好地了解滥用对哮喘的影响。
Childhood abuse has been found to be associated with adult-onset asthma; however, this association has not been studied in low and middle income countries with a high burden of gender-based violence, including childhood abuse. We examined the odds of asthma diagnosed at age 18 or older in relation to history of physical and sexual abuse among Peruvian pregnant women. This cross-sectional study collected demographic characteristics, history of abuse and asthma diagnoses from 3081 pregnant women. Logistic regression procedures estimated adjusted odds ratios and 95% confidence intervals (aOR,[95%CI]) for asthma diagnoses in relation to abuse. Overall, 71% of women reported a history of abuse (<18 years), and asthma was diagnosed among 2.6% of cohort participants. The prevalence of physical only, sexual only and both physical and sexual childhood abuse was 38%, 8% and 24%, respectively. History of physical only (1.16,[0.63–2.17]), sexual only (2.11,[0.92–4.84]) or both physical and sexual childhood abuse (1.75,[0.94–3.29]) were positively associated with increased odds of asthma, although the associations were not statistically significant in the multivariable analysis. However, the odds of asthma increased with increasing numbers of abuse events (ptrend=0.01). Women who reported ≥3 abuse events had an increased odds of asthma (1.88,[1.06–3.34]). Our results do not provide convincing evidence that childhood abuse is associated with asthma among pregnant Peruvian women; however, we were able to demonstrate that an increased number of abuse events are associated with asthma. Further research is required to better understand the effects of abuse on asthma.
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影响因子：
5
作者：
Gelaye B;Do N;Avila S;Carlos Velez J;Zhong QY;Sanchez SE;Peterlin BL;Williams MA
通讯作者：
Williams MA
童年时期的身体和性虐待与亲密伴侣的暴力，孕妇的一般健康状况不佳和抑郁症状的关联。
影响因子：
3.7
作者：
Barrios YV;Gelaye B;Zhong Q;Nicolaidis C;Rondon MB;Garcia PJ;Sanchez PA;Sanchez SE;Williams MA
通讯作者：
Williams MA
影响因子：
4.3
作者：
Laube, BL;Curbow, BA;Fitzgerald, ST
通讯作者：
Fitzgerald, ST
影响因子：
3.3
作者：
Scott, Kate M.;Smith, Don A. R.;Ellis, Pete M.
通讯作者：
Ellis, Pete M.
影响因子：
14.2
作者：
Coogan, Patricia F.;Wise, Lauren A.;Rosenberg, Lynn
通讯作者：
Rosenberg, Lynn