Toward a global virus genomic surveillance network.
Toward a global virus genomic surveillance network.
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DOI:
10.1016/j.chom.2023.03.003
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发表时间:
2023-06-14
影响因子:
30.3
通讯作者:
Grubaugh, Nathan D.
中科院分区:
文献类型:
--
作者:
Hill, Verity;Githinji, George;Vogels, Chantal B. F.;Bento, Ana I.;Chaguza, Chrispin;Carrington, Christine V. F.;Grubaugh, Nathan D.
The COVID-19 pandemic galvanized the field of virus genomic surveillance, demonstrating its utility for public health. Now, we must harness the momentum that led to increased infrastructure, training, and political will to build a sustainable global genomic surveillance network for other epidemic and endemic viruses. We suggest a generalizable modular sequencing framework wherein users can easily switch between virus targets to maximize cost-effectiveness and maintain readiness for new threats. We also highlight challenges associated with genomic surveillance and when global inequalities persist. We propose solutions to mitigate some of these issues, including training and multilateral partnerships. Exploring alternatives to clinical sequencing can also reduce the cost of surveillance programs. Finally, we discuss how establishing genomic surveillance would aid control programs and potentially provide a warning system for outbreaks, using a global respiratory virus (RSV), an arbovirus (dengue virus), and a regional zoonotic virus (Lassa virus) as examples. Following technological advancements from past emergencies, global virus genomic surveillance increased to unprecedented levels during the COVID-19 pandemic. In their perspective, Hill et al. examine this infrastructure and discuss the importance of developing sustainable global genomic surveillance networks for other epidemic and endemic viruses to inform public-health decision making.
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DOI:
10.1038/nrg.2017.88
发表时间:
2018-01
期刊:
Nature reviews. Genetics
影响因子:
--
作者:
Gardy JL;Loman NJ
通讯作者:
Loman NJ
DOI:
10.1126/science.aaf5036
发表时间:
2016-04-15
期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
Faria NR;Azevedo RDSDS;Kraemer MUG;Souza R;Cunha MS;Hill SC;Thézé J;Bonsall MB;Bowden TA;Rissanen I;Rocco IM;Nogueira JS;Maeda AY;Vasami FGDS;Macedo FLL;Suzuki A;Rodrigues SG;Cruz ACR;Nunes BT;Medeiros DBA;Rodrigues DSG;Queiroz ALN;da Silva EVP;Henriques DF;da Rosa EST;de Oliveira CS;Martins LC;Vasconcelos HB;Casseb LMN;Simith DB;Messina JP;Abade L;Lourenço J;Alcantara LCJ;de Lima MM;Giovanetti M;Hay SI;de Oliveira RS;Lemos PDS;de Oliveira LF;de Lima CPS;da Silva SP;de Vasconcelos JM;Franco L;Cardoso JF;Vianez-Júnior JLDSG;Mir D;Bello G;Delatorre E;Khan K;Creatore M;Coelho GE;de Oliveira WK;Tesh R;Pybus OG;Nunes MRT;Vasconcelos PFC
通讯作者:
Vasconcelos PFC
影响因子:
4.4
作者:
Gohl DM;Garbe J;Grady P;Daniel J;Watson RHB;Auch B;Nelson A;Yohe S;Beckman KB
通讯作者:
Beckman KB
影响因子:
13.6
作者:
Bhardwaj J;Hong S;Jang J;Han CH;Lee J;Jang J
通讯作者:
Jang J
影响因子:
6.4
作者:
HALL, CB;WALSH, EE;SCHNABEL, KC
通讯作者:
SCHNABEL, KC