Population genetic structure of Aedes polynesiensis in the Society Islands of French Polynesia: implications for control using a Wolbachia-based autocidal strategy.
Population genetic structure of Aedes polynesiensis in the Society Islands of French Polynesia: implications for control using a Wolbachia-based autocidal strategy.
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DOI：
10.1186/1756-3305-5-80
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发表时间：
2012-04-24
影响因子：
3.2
通讯作者：
Dobson SL
中科院分区：
文献类型：
--
作者：
Brelsfoard CL;Dobson SL
波利尼西亚伊蚊是南太平洋班氏吴策线虫的主要传播媒介，也是登革热病毒的重要传播媒介。需要更好地了解蚊子种群遗传学，以深入了解种群动态和传播，这有助于了解疾病传播的流行病学和媒介控制。鉴于潜在的释放沃尔巴克氏体感染株的媒介控制，我们的目标是调查的微地理和时间的人口遗传结构的A。法属波利尼西亚社会群岛内的波利尼西亚，并比较实验室菌株的遗传背景打算释放到其原产地的人口。一组8个微卫星位点用于基因型A。2005-2008年在法属波利尼西亚采集的A. polynesiensis和Aedes riversi实验室菌株。使用F-统计量、结构和AMOVA进行遗传分化的检查。BAYESASS用于估计蚊子移动的方向和速率。FST值，AMOVA和结构分析表明，从塔希提岛，Raiatea，和Maupiti多个采集点的岛内分化水平低。显著的成对FST值转化为更孤立的岛屿之间相对较小的岛间遗传分化水平，以及具有更大商业交通的岛屿之间几乎没有分化（即，塔希提岛、拉伊蒂亚岛和莫雷阿岛）。结构分析还表明，社会群岛上有两个种群，拟释放的沃尔巴克氏体感染菌株的遗传组成与其起源岛屿的野生型种群相似，而与A.里弗西。观察到的panmictic人口塔希提岛，Raiatea，和莫雷阿岛是一致的假设基因流之间发生的岛屿，有相对较高的水平的空中和海上交通，相比，更孤立的毛皮蒂和塔哈。基因流和潜在的蚊子运动进行了讨论，在有关试验中应用的自我杀灭策略。
Aedes polynesiensis is the primary vector of Wuchereria bancrofti in the South Pacific and an important vector of dengue virus. An improved understanding of the mosquito population genetics is needed for insight into the population dynamics and dispersal, which can aid in understanding the epidemiology of disease transmission and control of the vector. In light of the potential release of a Wolbachia infected strain for vector control, our objectives were to investigate the microgeographical and temporal population genetic structure of A. polynesiensis within the Society Islands of French Polynesia, and to compare the genetic background of a laboratory strain intended for release into its population of origin. A panel of eight microsatellite loci were used to genotype A. polynesiensis samples collected in French Polynesia from 2005-2008 and introgressed A. polynesiensis and Aedes riversi laboratory strains. Examination of genetic differentiation was performed using F-statistics, STRUCTURE, and an AMOVA. BAYESASS was used to estimate direction and rates of mosquito movement. FST values, AMOVA, and STRUCTURE analyses suggest low levels of intra-island differentiation from multiple collection sites on Tahiti, Raiatea, and Maupiti. Significant pair-wise FST values translate to relatively minor levels of inter-island genetic differentiation between more isolated islands and little differentiation between islands with greater commercial traffic (i.e., Tahiti, Raiatea, and Moorea). STRUCTURE analyses also indicate two population groups across the Society Islands, and the genetic makeup of Wolbachia infected strains intended for release is similar to that of wild-type populations from its island of origin, and unlike that of A. riversi. The observed panmictic population on Tahiti, Raiatea, and Moorea is consistent with hypothesized gene flow occurring between islands that have relatively high levels of air and maritime traffic, compared to that of the more isolated Maupiti and Tahaa. Gene flow and potential mosquito movement is discussed in relation to trials of applied autocidal strategies.
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影响因子：
3.2
作者：
Bataille, Arnaud;Cunningham, Andrew A.;Goodman, Simon J.
通讯作者：
Goodman, Simon J.
影响因子：
56.9
作者：
Chen, Chun-Hong;Huang, Haixia;Hay, Bruce A.
通讯作者：
Hay, Bruce A.
树突镜：大型系统发育树的互动观众。
影响因子：
3
作者：
Huson, Daniel H.;Richter, Daniel C.;Rausch, Christian;Dezulian, Tobias;Franz, Markus;Rupp, Regula
通讯作者：
Rupp, Regula
DOI：
10.1007/978-0-387-78225-6_9
发表时间：
2008-01-01
期刊：
TRANSGENESIS AND THE MANAGEMENT OF VECTOR-BORNE DISEASE
影响因子：
--
作者：
Bourtzis, Kostas
通讯作者：
Bourtzis, Kostas
DOI：
10.1073/pnas.1019295108
发表时间：
2011-03-22
影响因子：
11.1
作者：
de Valdez, Megan R. Wise;Nimmo, Derric;Black, William C.
通讯作者：
Black, William C.