Triterpenoids from the Herbs of Salicornia bigelovii.
Triterpenoids from the Herbs of Salicornia bigelovii.
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DOI:
10.3390/molecules201119695
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发表时间:
2015-11-12
期刊:
影响因子:
--
通讯作者:
Wang Q
中科院分区:
文献类型:
--
作者:
Shan Y;Li H;Guan F;Chen Y;Yin M;Wang M;Feng X;Wang Q
A new nortriterpene saponin, 3-O-β-d-glucuronopyranosyl-30-norolean-12,20(29)-dien-23-oxo-28-oic acid, namely bigelovii D (11), was isolated from the hydroalcoholic extract of herbs of Salicornia bigelovii along with 10 known saponins (1–10). Their chemical structures were identified on the basis of spectroscopic analyses including two-dimensional NMR and a comparison with literature data. Some of these compounds showed potent antifungal activities in vitro. Compounds 3, 4, 5, 6, 7, 10 and 11 demonstrated potent inhibitory activities against Colletotrichum gloeosporioides and compound 11 displayed broad-spectrum inhibitory activity against Alternaria alternata, A. solani, Botrytis cinerea, C. gloeosporioides, Fusarium graminearum, F. verticilloides, Thanatephorus cucumeris and Sclerotinia sclerotiorum, with EC50 values ranging from 13.6 to 36.3 μg/mL.
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