Mortality associated with nonrestorative short sleep or nonrestorative long time-in-bed in middle-aged and older adults.

Mortality associated with nonrestorative short sleep or nonrestorative long time-in-bed in middle-aged and older adults.
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DOI:
10.1038/s41598-021-03997-z
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发表时间:
2022-01-07
期刊:
影响因子:
4.6
通讯作者:
Kuriyama K
Kuriyama K
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Yoshiike T;Utsumi T;Matsui K;Nagao K;Saitoh K;Otsuki R;Aritake-Okada S;Suzuki M;Kuriyama K

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睡眠持续时间与人体健康的关系可能因睡眠是否具有恢复性而有所不同。利用5804名睡眠心脏健康研究参与者的数据,我们结合多导睡眠图测量的总睡眠时间(TST)或床上时间(TIB)(代表不同的睡眠行为),研究了睡眠安宁与全因死亡率的纵向关联。在中年人中,与休息的中间TST四分位数相比,感觉不休息的最低TST四分位数与较高的死亡率相关(风险比[HR], 1.54; 95%可信区间[CI] 1.01-2.33);感觉休息的最高TST四分位数与较低的死亡率相关(HR, 0.55; 95% CI 0.32-0.97)。在老年人中,与休息的中间TIB四分位数相比,感觉不休息的最高TIB四分位数与更高的死亡率相关(HR, 1.57; 95% CI 1.23-2.01)。结果表明,恢复性睡眠在区分睡眠时间对中年及以后健康结果的影响方面起着重要作用。
Associations of sleep duration with human health could differ depending on whether sleep is restorative. Using data from 5804 participants of the Sleep Heart Health Study, we examined the longitudinal association of sleep restfulness combined with polysomnography-measured total sleep time (TST) or time in bed (TIB), representing different sleeping behaviors, with all-cause mortality. Among middle-aged adults, compared with restful intermediate TST quartile, the lowest TST quartile with feeling unrested was associated with higher mortality (hazard ratio [HR], 1.54; 95% confidence interval [CI] 1.01–2.33); the highest TST quartile with feeling rested was associated with lower mortality (HR, 0.55; 95% CI 0.32–0.97). Among older adults, the highest TIB quartile with feeling unrested was associated with higher mortality, compared with restful intermediate TIB quartile (HR, 1.57; 95% CI 1.23–2.01). Results suggest a role of restorative sleep in differentiating the effects of sleep duration on health outcomes in midlife and beyond.
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