Fundus autofluorescence and optical coherence tomography findings in branch retinal vein occlusion.

Fundus autofluorescence and optical coherence tomography findings in branch retinal vein occlusion.
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DOI:
10.1155/2012/638064
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发表时间:
2012
影响因子:
1.9
通讯作者:
Sugano Y
Sugano Y
中科院分区:
医学4区
文献类型:
--
作者:
Sekiryu T;Iida T;Sakai E;Maruko I;Ojima A;Sugano Y

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目的。目的:描述视网膜分支静脉闭塞(BRVO)患者眼底自身荧光(FAF)和光学相干断层扫描(OCT)的表现。方法。在这个机构性的、回顾性的、观察性的病例系列中,对64例连续的BRVO患者的65只眼的FAF进行了评估,并与视力、OCT表现和其他临床观察结果进行了比较。结果。BRVO过程中出现了五种类型的自体荧光:(1)黄斑水肿区花瓣状的高自体荧光;(2)与视网膜下黄色沉积物重合的高自体荧光。(3)在浆液性视网膜脱离(SRD)区域内出现弥漫性高自体荧光,5/5(100%)眼的OCT显示视网膜下表面有沉淀。(4)视网膜出血消退后,静脉闭塞区显示弥漫性高自体荧光。(5)硬渗出物表现出高或低自身荧光。OCT显示大部分高自身荧光硬渗出位于视网膜色素上皮。结论。视网膜下间隙出现高自身荧光伴视网膜下积液或硬渗出。这种类型的高自身荧光可能归因于血细胞或巨噬细胞。FAF和OCT是非侵入性的方式,可提供BRVO引起的黄斑水肿的额外信息。
Purpose. To describe the findings of fundus autofluorescence (FAF) and optical coherence tomography (OCT) in patients with branch retinal vein occlusion (BRVO). Methods. In this institutional, retrospective, observational case series, FAF was evaluated in 65 eyes with BRVO in 64 consecutive patients and compared with visual acuity, OCT findings, and other clinical observations. Results. Five types of autofluorescence appeared during the course of BRVO: (1) petaloid-shaped hyperautofluorescence in the area of macular edema and (2) hyperautofluorescence coincident with yellow subretinal deposits. (3) Diffuse hyperautofluorescence appeared within the area of serous retinal detachment (SRD) and OCT showed precipitates on the undersurface of the retina in 5/5 of these eyes (100%). (4) The area of vein occlusion showed diffuse hyperautofluorescence after resolution of the retinal bleeding. (5) Hard exudates exhibited hyper- or hypoautofluorescence. OCT indicated that most of the hard exudates with hyperautofluorescence were located on the retinal pigment epithelium. Conclusions. Hyperautofluorescence associated with subretinal fluid or hard exudate appeared in the subretinal space. This type of hyperautofluorescence may be attributed to blood cell or macrophages. FAF and OCT are noninvasive modalities that provide additional information regarding macular edema due to BRVO.
DOI: 10.1159/000260229
发表时间: 2010-01-01
期刊: OPHTHALMOLOGICA
影响因子: 2.6
作者:
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发表时间: 2003-11-01
期刊: OPHTHALMOLOGY
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