Adult Exposures to Toxic Trace Elements as Measured in Nails along the Interoceanic Highway in the Peruvian Amazon.

Adult Exposures to Toxic Trace Elements as Measured in Nails along the Interoceanic Highway in the Peruvian Amazon.
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DOI:
10.3390/ijerph19106335
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发表时间:
2022-05-23
影响因子:
--
通讯作者:
Feingold BJ
Feingold BJ
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Pettigrew SM;Pan WK;Harrington J;Berky A;Rojas E;Feingold BJ

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砍伐森林、手工和小规模金矿开采以及与公路扩建相关的快速发展,给秘鲁马德雷德迪奥斯(MDD)的亚马逊地区带来了接触有毒微量元素的机会,该地区是世界上生物多样性最丰富的地方之一。这项研究的目的是评估Madre de Dios地区成年人对砷、镉、铅和汞的暴露情况。总共有418名成年人(18岁以上)参加了移民、环境和健康研究(IMAS)。同意书、调查数据和生物制品是在2014年8月至11月期间收集的。采用电感耦合等离子体扇区场质谱对指甲元素进行了测定。用单因素方差分析和线性混合模型检验了所选个体和家庭特征以及当地土地利用的差异。受ASGM影响地区的成年人指甲砷和指甲镉含量高于非ASGM地区的成年人。较高的家庭鱼类消费量与指甲汞和指甲铅呈正相关。结果表明,成人对砷、镉、铅和汞的暴露在Madre de Dios是不同的,与ASGM社区和鱼类消费相关的暴露表明,来自手工和小规模采矿的暴露在环境中是普遍存在的。有必要进行进一步调查,以确定对健康的潜在影响。
Deforestation, artisanal and small-scale gold mining (ASGM), and the rapid development related to highway expansion cause opportunities for toxic trace element exposure in the Amazon region of Madre de Dios (MDD), Peru, one of the most biologically diverse places in the world. The objective of this study was to assess the exposure to arsenic, cadmium, lead, and mercury among adults in Madre de Dios. In total, 418 adult (18+ years) participants in the Investigacion de Migracion, Ambiente, y Salud (IMAS) (Migration, Environment, and Health Study) participated in this study. Consent, survey data, and biospecimens were collected between August and November 2014. Nail elements were measured by inductively coupled plasma sector field mass spectrometry. Differences by selected individual and household characteristics and local land uses were tested using one-way ANOVAs and linear mixed models. Adults in ASGM-affected areas had higher nail arsenic and nail cadmium than their non-ASGM counterparts. Higher household fish consumption was positively associated with nail mercury and nail lead. The results indicate that adult exposure to arsenic, cadmium, lead, and mercury is heterogeneous across Madre de Dios, and the exposures related to ASGM communities and fish consumption suggest that exposures from artisanal and small-scale mining are environmentally widespread. Further investigation is warranted to ascertain potential health impacts.
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