Direct Visualization of Walking Motions of Photocontrolled Nanomachine on the DNA Nanostructure.
Direct Visualization of Walking Motions of Photocontrolled Nanomachine on the DNA Nanostructure.
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DOI：
10.1021/acs.nanolett.5b02502
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发表时间：
2015-10-14
期刊：
影响因子：
10.8
通讯作者：
Endo M
中科院分区：
文献类型：
--
作者：
Yang Y;Goetzfried MA;Hidaka K;You M;Tan W;Sugiyama H;Endo M
基于DNA支架构建了光驱动的人工分子纳米机器。芘修饰的步行链和二硫键连接的定子链用作支持步行者运动的锚定位点，被组装成 2D DNA 瓦片。 350 nm 光照射激发的芘分子诱导二硫键连接的定子链裂解，使 DNA 步行者能够从 DNA 平铺上的一个裂解定子迁移到下一个。观察助行器随时间变化的运动，并通过不同照射时间下助行器-定子复式在瓷砖上四个锚固点的分布来表征助行器的整个行走过程。重要的是，首先使用高速原子力显微镜 (HS-AFM) 在紫外线照射期间实时可视化 DNA 瓷砖上的光驱动机械运动。
A light-driven artificial molecular nanomachine was constructed based on DNA scaffolding. Pyrene-modified walking strands and disulfide bond-connected stator strands, employed as anchorage sites to support walker movement, were assembled into a 2D DNA tile. Pyrene molecules excited by photoirradiation at 350 nm induced cleavage of disulfide bond-connected stator strands, enabling the DNA walker to migrate from one cleaved stator to the next on the DNA tile. The time-dependent movement of the walker was observed and the entire walking process of the walker was characterized by distribution of the walker-stator duplex at four anchorage sites on the tile under different irradiation times. Importantly, the light-fuelled mechanical movements on DNA tile were first visualized in real time during UV irradiation using high-speed atomic force microscopy (HS-AFM).
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影响因子：
16.6
作者：
You, Mingxu;Chen, Yan;Zhang, Xiaobing;Liu, Haipeng;Wang, Ruowen;Wang, Kelong;Williams, Kathryn R;Tan, Weihong
通讯作者：
Tan, Weihong
DOI：
10.1073/pnas.211400898
发表时间：
2001-10-23
影响因子：
11.1
作者：
Ando, T;Kodera, N;Toda, A
通讯作者：
Toda, A
影响因子：
16.6
作者：
Bath, J;Green, SJ;Turberfield, AJ
通讯作者：
Turberfield, AJ
影响因子：
64.8
作者：
通讯作者：
--
影响因子：
17.1
作者：
You, Mingxu;Huang, Fujian;Chen, Zhuo;Wang, Ruo-Wen;Tan, Weihong
通讯作者：
Tan, Weihong