An evaluation of lower-body functional limitations among long-term survivors of 11 different types of cancers.
An evaluation of lower-body functional limitations among long-term survivors of 11 different types of cancers.
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DOI：
10.1002/cncr.24606
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发表时间：
2009-11-15
期刊：
影响因子：
6.2
通讯作者：
Jeffe, Donna B.
中科院分区：
文献类型：
--
作者：
Schootman, Mario;Aft, Rebecca;Jeffe, Donna B.
我们研究了长期（≥5年）癌症幸存者中下肢功能受限（LBFL）患病率增加的潜在原因（社会人口统计学、心理困扰、健康行为、慢性健康状况、医疗服务可及性）。使用2005-2007年全国健康访谈调查数据，我们将LBFL定义为报告有困难或无法进行至少5项活动中的1项（步行1/4英里；不休息地上下行走10步；站立2小时；弯腰、蹲下或跪下；举起10磅）。比较≥50名受访者（n= 2143）报告的11种癌症类型的长期幸存者（n= 2143）和无癌症史的患者（n= 72618）之间LBFL患病率的增加。在癌症幸存者中，57.0%的人患有LBFL，而对照组为26.6%。未调整的LBFL患病率因癌症类型而异，从44.9%（淋巴瘤幸存者）到88.8%（肺癌幸存者）不等。调整社会人口因素后，长期肺癌（比值比[OR]:7.91）、子宫癌（比值比：2.41）、甲状腺癌（比值比：2.27）、宫颈癌（比值比：1.76）、卵巢癌（比值比：1.75）和乳腺癌（比值比：1.35）幸存者报告LBFL的几率高于对照组（均p<0.05）。关节炎和腰痛的患病率以及获得医疗护理的差异解释了对照组和长期乳腺癌、宫颈癌、卵巢癌和子宫癌幸存者之间LBFL患病率的差异。作为对照，长期膀胱癌、结直肠癌、淋巴瘤、黑色素瘤和前列腺癌幸存者报告LBFL的可能性相同。治疗关节炎和腰痛以及增加获得医疗护理的机会可能有助于降低LBFL的风险，并改善特定长期癌症幸存者的生活质量。
We examined potential reasons (sociodemographics, psychological distress, health behavior, chronic health conditions, access to medical care) for increased prevalence of lower-body functional limitations (LBFL) among long-term (≥5 years) cancer survivors. Using 2005-2007 National Health Interview Survey data, we defined LBFL as reporting difficulty/inability to perform at least 1 of 5 activities (walking 1/4 of a mile; walking up and down 10 steps without rest; standing for 2 hours; stooping, crouching, or kneeling; and lifting 10 lbs). Increased prevalence of LBFL was compared between long-term survivors of each of 11 cancer types reported by ≥50 respondents (n=2,143) and persons without cancer history (controls; n=72,618). Among cancer survivors, 57.0% had a LBFL versus 26.6% of controls. The unadjusted prevalence of LBFL varied by cancer type, ranging from 44.9% (lymphoma survivors) to 88.8% (lung cancer survivors). Long-term lung (odds ratio [OR]:7.91), uterine (OR:2.41), thyroid (OR:2.27), cervical (OR:1.76), ovarian (OR:1.75), and breast (OR:1.35) cancer survivors had increased odds of reporting a LBFL than controls after adjusting for sociodemographic factors (all p<0.05). Differences in prevalence of arthritis and lower-back pain and in access to medical care explained differences in LBFL prevalence between controls and long-term breast, cervical, ovarian, and uterine cancer survivors. Long-term bladder, colorectal, lymphoma, melanoma, and prostate cancer survivors were equally likely to report a LBFL as controls. Treatment of arthritis and lower back pain and increasing access to medical care might help reduce the risk of LBFL and improve quality of life among specific long-term cancer survivors.
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DOI：
10.1111/j.1532-5415.2005.00507.x
发表时间：
2005-12-01
影响因子：
6.3
作者：
Keating, NL;Norredam, M;Meara, E
通讯作者：
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影响因子：
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作者：
Li, CR;Samsioe, G;Iosif, C
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DOI：
10.1093/gerona/60.2.207
发表时间：
2005-02-01
影响因子：
5.1
作者：
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通讯作者：
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影响因子：
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作者：
Balfour, JL;Kaplan, GA
通讯作者：
Kaplan, GA
DOI：
10.1016/j.ijrobp.2008.06.1905
发表时间：
2009-04-01
影响因子：
7
作者：
Korfage, Ida J.;Essink-Bot, Marie-Louise;van Ballegooijen, Marjolein
通讯作者：
van Ballegooijen, Marjolein