Experimental evaluation of analgesic and anti-inflammatory potential of Oyster mushroom Pleurotus florida.
Experimental evaluation of analgesic and anti-inflammatory potential of Oyster mushroom Pleurotus florida.
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DOI：
10.4103/0253-7613.106438
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发表时间：
2013-01
影响因子：
2.4
通讯作者：
Rai G
中科院分区：
文献类型：
--
作者：
Ganeshpurkar A;Rai G
食用蘑菇被用作美味的食物和健康营养补充剂已有几个世纪的历史。在许多蘑菇物种中已经鉴定出许多生物活性分子，以在Wistar大鼠中使用各种实验模型来评估牡蛎蘑菇佛罗里达州的镇痛和抗炎潜力。进行了急性毒性研究，其中选择250 mg/ kg和500 mg/kg的剂量用于本研究。采用热板法、甩尾法、乙酸诱导的大鼠扭体法和福尔马林诱导的大鼠疼痛法测定镇痛活性，同时使用角叉菜胶诱导炎症并进行抗炎研究。HEE对所有实验模型均显示出显著的镇痛和抗炎作用（P < 0.01）。这些研究得出结论，佛罗里达具有镇痛和抗炎潜力，这可能是由于存在的肌化学物质，如黄酮类化合物，酚类化合物和多糖。
Edible mushrooms have been used as flavorful foods and as health nutritional supplements for several centuries. A number of bioactive molecules have been identified in numerous mushroom species To evaluate the analgesic and anti-inflammatory potential of Oyster Mushroom Pleurotus florida using various experimental models in Wistar rats. Acute toxicity studies were performed whereby dose of 250 mg/ kg and 500 mg/kg was selected for present study, Analgesic activity was determined using hot plate method, tail flick method, acetic acid induced writhing and formalin induced pain in rats, while carrageenan was used to induce inflammation and anti-inflammatory studies were performed. HEE showed significant (P < 0.01) analgesic and anti-inflammatory response against all experimental models. These studies conclude that Pleurotus florida possesses analgesic and anti- inflammatory potential which might be due to presence of myochemicals like flavonoids, phenolics and polysaccharides.
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影响因子：
7.3
作者：
COLLIER, HOJ;DINNEEN, LC;SCHNEIDER, C
通讯作者：
SCHNEIDER, C
影响因子：
5.4
作者：
Dharmasiri, MG;Jayakody, JRAC;Ratnasooriya, WD
通讯作者：
Ratnasooriya, WD
影响因子：
3.4
作者：
Borgi, W.;Ghedira, K.;Chouchane, N.
通讯作者：
Chouchane, N.
影响因子：
5
作者：
Godoy, MCM;Fighera, MR;Mello, CF
通讯作者：
Mello, CF
牡蛎蘑菇胸膜佛罗里达菌在孤立的山羊眼镜上提取物的体外预防白内障。
影响因子：
2.4
作者：
Ganeshpurkar A;Bhadoriya SS;Pardhi P;Jain AP;Rai G
通讯作者：
Rai G