Maternal pregnancy-specific anxiety is associated with child executive function at 6-9 years age.

Maternal pregnancy-specific anxiety is associated with child executive function at 6-9 years age.
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DOI:
10.3109/10253890.2011.623250
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发表时间:
2011-11
期刊:
Stress (Amsterdam, Netherlands)
影响因子:
--
通讯作者:
Sandman CA
Sandman CA
中科院分区:
其他
文献类型:
--
作者:
Buss C;Davis EP;Hobel CJ;Sandman CA

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由于胎儿大脑发育速度极快,早期生活经历有可能改变神经发育的轨迹,这可能会增加对发育和神经精神疾病的易感性。有证据表明,产前母亲的压力和焦虑,特别是与怀孕有关的担忧,会影响神经发育结果。在当前的前瞻性纵向研究中,我们纳入了89名妇女,她们在妊娠15、19、25、31和37周时有妊娠特异性焦虑、状态焦虑和抑郁的系列数据。当目标怀孕的后代在6到9岁之间时,他们的执行功能被评估。在怀孕期间,高水平的平均母亲怀孕特异性焦虑与女孩的抑制控制较低以及男孩和女孩的视觉空间工作记忆表现较低有关。高状态的焦虑和抑郁也与较低的视觉空间工作记忆表现有关。然而,在考虑了怀孕特异性焦虑之后,状态焦虑和抑郁都不能解释任何额外的差异。这些发现有助于文献支持怀孕特异性焦虑和认知发展之间的联系,并扩展了我们对这种影响持续到童年中期的认识。
Because fetal brain development proceeds at an extremely rapid pace, early life experiences have the potential to alter the trajectory of neurodevelopment, which may increase susceptibility for developmental and neuropsychiatric disorders. There is evidence that prenatal maternal stress and anxiety, especially worries specifically related to being pregnant, influence neurodevelopmental outcomes. In the current prospective longitudinal study, we included 89 women for whom serial data were available for pregnancy-specific anxiety, state anxiety, and depression at 15, 19, 25, 31, and 37 weeks gestation. When the offspring from the target pregnancy were between 6 and 9 years of age, their executive function was assessed. High levels of mean maternal pregnancy-specific anxiety over the course of gestation were associated with lower inhibitory control in girls only and lower visuospatial working memory performance in boys and girls. Higher-state anxiety and depression also were associated with lower visuospatial working memory performance. However, neither state anxiety nor depression explained any additional variance after accounting for pregnancy-specific anxiety. The findings contribute to the literature supporting an association between pregnancy-specific anxiety and cognitive development and extend our knowledge about the persistence of this effect until middle childhood.
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