Fixation eye movement abnormalities and stereopsis recovery following strabismus repair.
Fixation eye movement abnormalities and stereopsis recovery following strabismus repair.
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DOI：
10.1038/s41598-021-93919-w
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发表时间：
2021-07-13
影响因子：
4.6
通讯作者：
Ghasia FF
中科院分区：
文献类型：
--
作者：
Martin TL;Murray J;Garg K;Gallagher C;Shaikh AG;Ghasia FF
我们评价了斜视修复对融合性发育不良眼球震颤(FMN)患者和无眼球震颤患者凝视性眼动(FEMS)和立体视恢复的影响。对21例斜视患者、12例FMN患者和9例无眼球震颤患者进行了斜视矫正手术前后的检查。在单目观察条件下，眼球运动被记录在凝视任务中。分析观察眼和非观察眼的FEMS和双变量轮廓椭圆面积(BCEA)。斜视修复术改善了FMN患者和非FMN患者的斜视角度，但无眼球震颤的患者立体视有改善的可能性更大。在无眼球震颤的受试者中，斜视矫正后双眼的凝视性眼跳幅度和眼球间漂移速度降低。与无眼球震颤的患者相比，FMN患者的慢相速度更高。两组术后BCEA均无明显变化。在没有眼球震颤的患者中，双眼功能(立体视)的改善，以及凝视眼跳幅度和眼球间漂移速度的降低，可能至少部分归因于通过手术调整眼睛而实现的中枢适应机制。FMN患者斜视修复后没有改善可能表明早发性婴儿斜视患者缺乏这种适应机制。凝视眼球运动特征的评估是预测斜视矫正术后功能改善的有用工具。
We evaluated the effects of strabismus repair on fixational eye movements (FEMs) and stereopsis recovery in patients with fusion maldevelopment nystagmus (FMN) and patients without nystagmus. Twenty-one patients with strabismus, twelve with FMN and nine without nystagmus, were tested before and after strabismus repair. Eye-movements were recorded during a gaze-holding task under monocular viewing conditions. Fast (fixational saccades and quick phases of nystagmus) and slow (inter-saccadic drifts and slow phases of nystagmus) FEMs and bivariate contour ellipse area (BCEA) were analyzed in the viewing and non-viewing eye. Strabismus repair improved the angle of strabismus in subjects with and without FMN, however patients without nystagmus were more likely to have improvement in stereoacuity. The fixational saccade amplitudes and intersaccadic drift velocities in both eyes decreased after strabismus repair in subjects without nystagmus. The slow phase velocities were higher in patients with FMN compared to inter-saccadic drifts in patients without nystagmus. There was no change in the BCEA after surgery in either group. In patients without nystagmus, the improvement of the binocular function (stereopsis), as well as decreased fixational saccade amplitude and intersaccadic drift velocity, could be due, at least partially, to central adaptive mechanisms rendered possible by surgical realignment of the eyes. The absence of improvement in patients with FMN post strabismus repair likely suggests the lack of such adaptive mechanisms in patients with early onset infantile strabismus. Assessment of fixation eye movement characteristics can be a useful tool to predict functional improvement post strabismus repair.
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DOI：
10.1126/science.1166112
发表时间：
2009-02-13
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Hafed ZM;Goffart L;Krauzlis RJ
通讯作者：
Krauzlis RJ
伴有或不伴有融合发育不良性眼球震颤的弱视患者的单眼和双眼视觉功能缺陷。
影响因子：
4.4
作者：
Murray J;Garg K;Ghasia F
通讯作者：
Ghasia F
影响因子：
1.8
作者：
Bucci, Maria Pia;Bremond-Gignac, Dominique;Kapoula, Zoi
通讯作者：
Kapoula, Zoi
DOI：
10.1146/annurev-vision-111815-114335
发表时间：
2016-01-01
期刊：
ANNUAL REVIEW OF VISION SCIENCE, VOL 2
影响因子：
--
作者：
Das, Vallabh E.
通讯作者：
Das, Vallabh E.
影响因子：
5.5
作者：
BARLOW, HB
通讯作者：
BARLOW, HB