A 5-Year Review of Senecavirus A in China since Its Emergence in 2015.

A 5-Year Review of Senecavirus A in China since Its Emergence in 2015.
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自2015年出现以来,对中国的塞氏病毒A进行了5年的评论。

DOI:
10.3389/fvets.2020.567792
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发表时间:
2020
影响因子:
3.2
通讯作者:
Shan H
Shan H
中科院分区:
农林科学2区
文献类型:
--
作者:
Liu F;Wang Q;Huang Y;Wang N;Shan H

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塞内卡病毒A (SVA),以前称为塞内卡谷病毒,属于小核糖核酸病毒科塞内卡病毒属。这种病毒可引起猪的水疱病和流行性短暂的新生儿死亡。典型的临床症状包括口鼻部、口腔粘膜、冠状带和蹄上的水疱和/或溃疡性病变。 SVA于2015年在中国广东省兴起,此后逐渐扩展到其他省、自治区和直辖市(P.A.M.s)。目前已有超过一半的P.A.M.感染了SVA,部分地区还出现了无症状感染者。系统发育分析显示,中国分离株聚集成五个遗传分支,这意味着自2015年SVA出现以来,进化速度很快。本文介绍了有关中国SVA感染的最新知识,包括其历史、流行病学、进化特征、诊断和疫苗。
Senecavirus A (SVA), previously known as Seneca Valley virus, is classified into the genus Senecavirus in the family Picornaviridae. This virus can cause vesicular disease and epidemic transient neonatal losses in swine. Typical clinical signs include vesicular and/or ulcerative lesions on the snout, oral mucosa, coronary bands and hooves. SVA emerged in Guangdong Province of China in 2015, and thereafter gradually spread into other provinces, autonomous regions and municipalities (P.A.M.s). Nowadays more than half of the P.A.M.s have been affected by SVA, and asymptomatic infection has occurred in some areas. The phylogenetic analysis shows that China isolates are clustered into five genetic branches, implying a fast evolutionary speed since SVA emergence in 2015. This review presented current knowledge concerning SVA infection in China, including its history, epidemiology, evolutionary characteristics, diagnostics and vaccines.
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