Physical localization of the mouse aryl hydrocarbon receptor nuclear translocator-2 (Arnt2) gene within the c112K deletion.
Physical localization of the mouse aryl hydrocarbon receptor nuclear translocator-2 (Arnt2) gene within the c112K deletion.
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小鼠芳烃受体核易位子 2 (Arnt2) 基因在 c112K 缺失内的物理定位。
DOI：
10.1006/geno.1998.5347
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发表时间：
1998
期刊：
影响因子：
4.4
通讯作者：
Holdener,BC
中科院分区：
文献类型：
--
作者：
Wines,ME;Tiffany,AM;Holdener,BC
The albino deletions identify at least seven functional intervals essential for pre- and postnatal development in the 6- to 10-cM region surrounding thealbino coat color(c = tyrosinase) locus on mouse chromosome 7. Thec112Kdeletion identifies a putative thymus functional region not removed by the overlappingc3Hdeletion. Cloning thec3Hproximal breakpoint provided a starting point for construction of an 840-kb BAC contig spanning thec112Kandc3H(D7Ssb3Hp) proximal breakpoints. These breakpoints are separated by 320–350 kb. Thearyl hydrocarbon receptor nuclear translocator-2 (Arnt2)is completely removed by thec112Kdeletion and spans 130–170 kb of the interval. AlthoughArnt2is a candidate for the thymus defects inc112Khomozygotes, the possibility that other as yet unidentified genes in thec112Kdeletion are responsible for the abnormalities has not been ruled out.Arnt2is a member of the bHLH-PAS (Per, Ahr, Arnt, Sim) family of transcription factors and shares the highest similarity withArnt.The survival ofc112Khomozygotes markedly contrasts the embryonic lethality observed inArnt-deficient embryos and suggests distinct roles for these related transcription factors during embryogenesis.
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人类遗传性酪氨酸血症 I 的小鼠模型。
DOI：
10.1002/bies.950160203
发表时间：
1994
期刊：
BioEssays : news and reviews in molecular, cellular and developmental biology
影响因子：
--
作者：
B. Holdener;T. Magnuson
通讯作者：
T. Magnuson
对小鼠白化缺失复合物进行物理定位，以定位 alf/hsdr-1（新生儿存活所需的基因座）。
影响因子：
4.4
作者：
Kelsey,G;Schedl,A;Ruppert,S;Niswander,L;Magnuson,T;Klebig,ML;Rinchik,EM;Schütz,G
通讯作者：
Schütz,G
从侧翼标记的染色体跳跃定义了白化缺失复合体中 alf/hsdr-1 的最小区域。
影响因子：
4.4
作者：
Schedl,A;Ruppert,S;Kelsey,G;Thies,E;Niswander,L;Magnuson,T;Klebig,ML;Rinchik,EM;Schütz,G
通讯作者：
Schütz,G
影响因子：
2.7
作者：
Kozak, KR;Abbott, B;Hankinson, O
通讯作者：
Hankinson, O
DOI：
10.1101/sqb.1951.016.01.024
发表时间：
1951-01-01
期刊：
COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY
影响因子：
--
作者：
RUSSELL, WL
通讯作者：
RUSSELL, WL