The nucleus accumbens is involved in both the pursuit of social reward and the avoidance of social punishment.
The nucleus accumbens is involved in both the pursuit of social reward and the avoidance of social punishment.
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DOI：
10.1016/j.neuropsychologia.2013.07.020
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发表时间：
2013-09
期刊：
影响因子：
2.6
通讯作者：
Schultz, Robert T.
中科院分区：
文献类型：
--
作者：
Kohls, Gregor;Perino, Michael T.;Taylor, James M.;Madva, Elizabeth N.;Cayless, Sarah J.;Troiani, Vanessa;Price, Elinora;Faja, Susan;Herrington, John D.;Schultz, Robert T.
人类的社会动机以追求社会回报和逃避社会惩罚为特征。特别是腹侧纹状体/伏隔核(VS/NACC)，与社会动机的奖励成分有关，即对社会激励的渴望，如认可。然而，目前尚不清楚VS/NACC在多大程度上参与了避免反对等社会惩罚的工作，这是一个本质上令人愉快的结果。因此，我们进行了一项事件相关功能磁共振成像(FMRI)研究，使用动态视频刺激而不是静态图片作为社会激励延迟任务，以考察参与者获得社会奖励和避免社会惩罚的动机。正如预测的那样，对可避免的社会惩罚(即不认可)的预期招募了VS/NACC，其方式类似于在预期社会奖励获得(即认可)时观察到的VS/NACC激活。更强的VS/NACC活性伴随着参与者获得这些预期结果的更快的反应时间。这一数据支持这样一种假设，即动态的社会激励会引发强大的VS/NACC活动，这可能反映了获得社会奖励和避免社会惩罚的动机。关于VS/NACC参与自闭症和社交恐惧症的社会动机功能障碍的临床意义进行了讨论。
Human social motivation is characterized by the pursuit of social reward and the avoidance of social punishment. The ventral striatum/nucleus accumbens (VS/Nacc), in particular, has been implicated in the reward component of social motivation, i.e., the ‘wanting’ of social incentives like approval. However, it is unclear to what extent the VS/Nacc is involved in avoiding social punishment like disapproval, an intrinsically pleasant outcome. Thus, we conducted an event-related functional magnetic resonance imaging (fMRI) study using a social incentive delay task with dynamic video stimuli instead of static pictures as social incentives in order to examine participants' motivation for social reward gain and social punishment avoidance. As predicted, the anticipation of avoidable social punishment (i.e., disapproval) recruited the VS/Nacc in a manner that was similar to VS/Nacc activation observed during the anticipation of social reward gain (i.e., approval). Stronger VS/Nacc activity was accompanied by faster reaction times of the participants to obtain those desired outcomes. This data support the assumption that dynamic social incentives elicit robust VS/Nacc activity, which likely reflects motivation to obtain social reward and to avoid social punishment. Clinical implications regarding the involvement of the VS/Nacc in social motivation dysfunction in autism and social phobia are discussed.
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影响因子：
4.7
作者：
Carlezon WA Jr;Thomas MJ
通讯作者：
Thomas MJ
DOI：
10.1037/h0042880
发表时间：
1958-01-01
期刊：
JOURNAL OF ABNORMAL AND SOCIAL PSYCHOLOGY
影响因子：
--
作者：
GEWIRTZ, JL;BAER, DM
通讯作者：
BAER, DM
影响因子：
4.8
作者：
Fox, Christopher J.;Iaria, Giuseppe;Barton, Jason J. S.
通讯作者：
Barton, Jason J. S.
影响因子：
2.9
作者：
Falk EB;Way BM;Jasinska AJ
通讯作者：
Jasinska AJ
DOI：
10.1196/annals.1412.007
发表时间：
2007-01-01
期刊：
SOCIAL COGNITIVE NEUROSCIENCE OF ORGANIZATIONS
影响因子：
--
作者：
Caldu, Xavier;Dreher, Jean-Claude
通讯作者：
Dreher, Jean-Claude