An imaging genetics approach to understanding social influence.
An imaging genetics approach to understanding social influence.
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DOI：
10.3389/fnhum.2012.00168
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发表时间：
2012
影响因子：
2.9
通讯作者：
Jasinska AJ
中科院分区：
文献类型：
--
作者：
Falk EB;Way BM;Jasinska AJ
规范的社会影响几乎塑造了我们生活的各个方面，但介导这些社会影响对行为影响的生物过程仍然不完全清楚。在这个假设中，我们概述了一个理论框架和一个综合的研究方法来研究社会对大脑的影响和这种影响的遗传调节。首先，我们回顾了神经影像学证据，将社会影响力和顺从性与大脑的奖励系统联系起来。接下来，我们将回顾将社会惩罚（排斥）与参与疼痛体验的大脑系统联系起来的神经影像学证据，以及将排斥与顺从联系起来的证据。我们认为，增加对社会线索的敏感性的遗传变异可能使个体对社会奖励或惩罚（或可能两者）更敏感，这反过来又增加了更广泛的规范性社会影响的一致性和易感性。为此，我们回顾了大脑神经化学反应的遗传调节剂的证据，并提出了基因和药理学可能调节对社会影响的敏感性的方法。最后，我们提出了一个综合成像遗传学的方法来研究大脑介质和遗传调节剂的各种社会影响人类的态度，信仰和行动。
Normative social influences shape nearly every aspect of our lives, yet the biological processes mediating the impact of these social influences on behavior remain incompletely understood. In this Hypothesis, we outline a theoretical framework and an integrative research approach to the study of social influences on the brain and genetic moderators of such effects. First, we review neuroimaging evidence linking social influence and conformity to the brain's reward system. We next review neuroimaging evidence linking social punishment (exclusion) to brain systems involved in the experience of pain, as well as evidence linking exclusion to conformity. We suggest that genetic variants that increase sensitivity to social cues may predispose individuals to be more sensitive to either social rewards or punishments (or potentially both), which in turn increases conformity and susceptibility to normative social influences more broadly. To this end, we review evidence for genetic moderators of neurochemical responses in the brain, and suggest ways in which genes and pharmacology may modulate sensitivity to social influences. We conclude by proposing an integrative imaging genetics approach to the study of brain mediators and genetic modulators of a variety of social influences on human attitudes, beliefs, and actions.
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影响因子：
16.2
作者：
Baliki, Marwan N.;Geha, Paul Y.;Fields, Howard L.;Apkarian, A. Vania
通讯作者：
Apkarian, A. Vania
影响因子：
7.6
作者：
Campbell-Meiklejohn, Daniel K.;Simonsen, Arndis;Roepstorff, Andreas
通讯作者：
Roepstorff, Andreas
影响因子：
7.6
作者：
BOIVIN, M;DODGE, KA;COIE, JD
通讯作者：
COIE, JD
DOI：
10.1196/annals.1412.007
发表时间：
2007-01-01
期刊：
SOCIAL COGNITIVE NEUROSCIENCE OF ORGANIZATIONS
影响因子：
--
作者：
Caldu, Xavier;Dreher, Jean-Claude
通讯作者：
Dreher, Jean-Claude
影响因子：
3.3
作者：
Cacioppo, JT;Hawkley, LC;Berntson, GG
通讯作者：
Berntson, GG