Gender differences in the prevalence of heroin and opioid analgesic misuse in the United States, 2015-2019.
Gender differences in the prevalence of heroin and opioid analgesic misuse in the United States, 2015-2019.
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DOI：
10.1016/j.drugalcdep.2021.108978
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发表时间：
2021-10-01
影响因子：
4.2
通讯作者：
Greenfield SF
中科院分区：
文献类型：
--
作者：
McHugh RK;Nguyen MD;Chartoff EH;Sugarman DE;Greenfield SF
类阿片滥用流行率的性别差异继续演变，近年来尚未得到很好的定性。我们的目标是调查2015-2019年5年期间美国阿片类药物滥用和使用障碍患病率的性别差异。我们使用2015-2019年全国药物使用和健康调查的年度调查数据来估计阿片类药物滥用流行率的性别差异。我们检查了过去一年阿片类镇痛药滥用开始，阿片类镇痛药滥用，海洛因使用，阿片类镇痛药使用障碍和海洛因使用障碍。Logistic回归模型用于测试性别差异，调整社会人口变量。在调整后的分析中，与男性相比，女性在过去一年中开始滥用阿片类镇痛药的几率更高。相比之下，男性滥用阿片类镇痛药、海洛因使用和阿片类镇痛药或海洛因使用障碍的几率更高。虽然阿片类药物滥用历来在男性中更为普遍，但阿片类镇痛剂滥用的性别差异继续缩小，开始滥用的女性多于男性，包括少女滥用率较高。男性使用海洛因的比例仍然是女性的两倍左右。
Gender differences in the prevalence of opioid misuse continue to evolve and have not been well characterized in recent years. Our objective was to investigate gender differences in the prevalence of opioid misuse and use disorder in the US over the 5-year period from 2015–2019. We used annual survey data from the 2015–2019 National Survey on Drug Use and Health to estimate gender differences in the prevalence of opioid misuse. We examined past-year opioid analgesic misuse initiation, opioid analgesic misuse, heroin use, opioid analgesic use disorder and heroin use disorder. Logistic regression models were used to test gender differences, adjusting for sociodemographic variables. In adjusted analyses, women had higher odds of having initiated opioid analgesic misuse in the past year compared to men. In contrast, men had higher odds of misuse of opioid analgesics, heroin use, and an opioid analgesic or heroin use disorder. Although opioid misuse has historically been more prevalent in men, the gender difference in opioid analgesic misuse continues to narrow, with more women initiating misuse than men including higher rates of misuse in adolescent girls. Heroin use continues to be approximately twice as common in men as women.
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