A cross-sectional study on the association between vitamin D levels and caries in the permanent dentition of Korean children.

A cross-sectional study on the association between vitamin D levels and caries in the permanent dentition of Korean children.
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DOI:
10.1186/s12903-018-0505-7
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发表时间:
2018-03-13
期刊:
影响因子:
2.9
通讯作者:
Oh HW
Oh HW
中科院分区:
医学3区
文献类型:
--
作者:
Kim IJ;Lee HS;Ju HJ;Na JY;Oh HW

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加拿大最近的一项研究报告称,维生素D缺乏与龋齿有关。由于韩国人被报道缺乏维生素D,我们调查了韩国儿童龋齿与血清维生素D水平降低的关系。本研究的目的是分析朝鲜族恒牙期儿童血液中维生素D[25(OH)D]浓度与龋齿的关系。数据收集自2008-2013年进行的韩国国民健康和营养检查调查。共有1688名儿童(10-12岁)入学。通过分析25-羟基维生素D[25(OH)D]水平来测量维生素D摄入量。使用龋齿缺失充填指数(DMFT)和龋损缺失充填(DMF)率来评估恒牙期的龋病经历。统计分析包括复杂样本卡方检验、复杂样本Logistic回归分析和皮尔逊相关分析。25(OH)D水平低于50nmol/L组恒牙期和恒第一磨牙患龋率高于25(OH)D水平50nmol/L或以上组。当控制性别等外部因素时,25(OH)D水平与龋病无显著相关性,但与第一磨牙龋病显著相关。25(OH)D水平低于50nmol/L的儿童患第一磨牙龋病的可能性是25(OH)D水平为50nmol/L或以上的儿童的1.295倍。此外,25(OH)D水平与DMFT呈负相关,但相关程度不强。25(OH)D与龋齿的关系尚不清楚。然而,我们的发现表明,维生素D不足可能是龋齿的一个危险因素。
A recent study in Canada reported that vitamin D deficiency is associated with dental caries. Because Koreans have been reported to be deficient in vitamin D, we investigated the relationship between dental caries and reduced serum vitamin D levels in Korean children. The purpose of this study was to analyze the relationships between blood vitamin D [25(OH)D] concentrations and dental caries in the permanent dentition of Korean children. Data were collected from the Korea National Health and Nutrition Examination Survey performed in 2008–2013. A total of 1688 children (10–12 years of age) were enrolled. Vitamin D intake was measured through analysis of 25-hydroxy vitamin D [25(OH)D] levels. Caries experience in permanent dentition was assessed using the decay-missing-filled teeth (DMFT) index and decayed-missing-filled (DMF) rate. Statistical analyses included complex samples Chi-square tests, complex samples logistic regression analyses, and Pearson’s correlations. The group with 25(OH) D levels lower than 50 nmol/L had a higher proportion of children with caries in the permanent dentition and permanent first molar than the group with 25(OH)D levels of 50 nmol/L or more. When external factors, such as sex, were controlled, 25(OH)D levels were not significantly correlated with caries, but were significantly correlated with first molar caries. Children with 25(OH)D levels lower than 50 nmol/L were 1.295 times more likely to have first molar caries than those with 25(OH)D levels of 50 nmol/L or more. Additionally, 25(OH)D levels and DMFT were negatively correlated; however, the degree of correlation was not strong. The association between 25(OH)D and dental caries is still not clear. However, our findings suggested that vitamin D insufficiency may be a risk factor for dental caries.
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