Optical trapping assisted detection rate enhancement of single molecules on a nanopore optofluidic chip.
Optical trapping assisted detection rate enhancement of single molecules on a nanopore optofluidic chip.
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DOI:
10.1364/optica.6.001130
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发表时间:
2019-09-20
期刊:
影响因子:
10.4
通讯作者:
Schmidt H
中科院分区:
文献类型:
--
作者:
Rahman M;Harrington M;Stott MA;Li Y;Sampad MJN;Yuzvinsky TD;Hawkins AR;Schmidt H
We use optical trapping to deliver molecular targets to the vicinity of a nanopore for high-throughput single molecule analysis on an optofluidic chip. DNA detection rates increase over 80× to enable detection at attomolar concentrations.
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