Spatial-temporal heterogeneity in malaria receptivity is best estimated by vector biting rates in areas nearing elimination.
Spatial-temporal heterogeneity in malaria receptivity is best estimated by vector biting rates in areas nearing elimination.
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DOI：
10.1186/s13071-018-3201-1
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发表时间：
2018-11-27
影响因子：
3.2
通讯作者：
Russell TL
中科院分区：
文献类型：
--
作者：
Burkot TR;Bugoro H;Apairamo A;Cooper RD;Echeverry DF;Odabasi D;Beebe NW;Makuru V;Xiao H;Davidson JR;Deason NA;Reuben H;Kazura JW;Collins FH;Lobo NF;Russell TL
在消灭疟疾后何时可以撤销媒介控制的决定取决于一个地区支持媒介种群的接受度或潜力。为了指导疟疾控制和消除方案，在所罗门群岛西部省活跃传播的地理位置的村庄内部和之间，比较了叮咬率、子孢子率、昆虫学接种率和胎胎率来估计疟疾接受度和传播率的潜力。疟疾的传播和传播潜力在时间和空间上都是不同的，无论是在村庄之间还是在村庄内，都是由按蚊的种类组成和叮咬密度所确定的。在叮咬高峰期(18：00~00：00 h)，法氏按蚊的咬合率从低接受度村庄的每人每半晚不到0.3口，到高接受度村庄的每人26口不等。在村庄内，按蚊叮咬率较高的地点显著聚集。子孢子率为恶性疟原虫、间日疟原虫和卵形疟原虫的持续传播提供了证据。法拉蒂和因牵涉到一名。鼻吸虫作为一种次要媒介，但作为传播强度的指标并不可靠。在研究的低传播区，无法以为疟疾规划提供指导所需的精度测量子孢子、昆虫学接种率和产仔率。通过媒介咬合率可以最可靠地估计病毒的接受性和潜在的传播风险。这些结果支持对业务研究方案进行有意义的设计，以确保资源集中于提供可供疟疾控制方案利用的信息，以便更好地了解不同地区的传播、传播风险和接受度。
Decisions on when vector control can be withdrawn after malaria is eliminated depend on the receptivity or potential of an area to support vector populations. To guide malaria control and elimination programmes, the potential of biting rates, sporozoite rates, entomological inoculation rates and parity rates to estimate malaria receptivity and transmission were compared within and among geographically localised villages of active transmission in the Western Province of the Solomon Islands. Malaria transmission and transmission potential was heterogeneous in both time and space both among and within villages as defined by anopheline species composition and biting densities. Biting rates during the peak biting period (from 18:00 to 00:00 h) of the primary vector, Anopheles farauti, ranged from less than 0.3 bites per person per half night in low receptivity villages to 26 bites per person in highly receptive villages. Within villages, sites with high anopheline biting rates were significantly clustered. Sporozoite rates provided evidence for continued transmission of Plasmodium falciparum, P. vivax and P. ovale by An. farauti and for incriminating An. hinesorum, as a minor vector, but were unreliable as indicators of transmission intensity. In the low transmission area studied, sporozoite, entomological inoculation and parity rates could not be measured with the precision required to provide guidance to malaria programmes. Receptivity and potential transmission risk may be most reliably estimated by the vector biting rate. These results support the meaningful design of operational research programmes to ensure that resources are focused on providing information that can be utilised by malaria control programmes to best understand both transmission, transmission risk and receptivity across different areas.
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影响因子：
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通讯作者：
McKenzie FE
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Snow, Robert William
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Cohen JM;Moonen B;Snow RW;Smith DL
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Smith DL
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BRYAN, JH
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通讯作者：
Cooper, Robert D.