Comparative efficacy of the generalized anxiety disorder 7-item scale and the Edinburgh Postnatal Depression Scale as screening tools for generalized anxiety disorder in pregnancy and the postpartum period.

Comparative efficacy of the generalized anxiety disorder 7-item scale and the Edinburgh Postnatal Depression Scale as screening tools for generalized anxiety disorder in pregnancy and the postpartum period.
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DOI:
10.1177/070674371405900806
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发表时间:
2014-08
期刊:
Canadian journal of psychiatry. Revue canadienne de psychiatrie
影响因子:
--
通讯作者:
Frey BN
Frey BN
中科院分区:
其他
文献类型:
--
作者:
Simpson W;Glazer M;Michalski N;Steiner M;Frey BN

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大约24.1%的孕妇患有至少一种焦虑症,其中8.5%患有广泛性焦虑症(GAD)。GAD通常与重度抑郁症(MDD)有关。在围产期,身体和躯体症状的存在往往使抑郁症和焦虑症之间的区分更具挑战性。迄今为止,还没有开发出筛查工具来检测围产期人群中的GAD。我们调查了GAD 7项量表(GAD-7)作为孕妇和产后妇女GAD筛查工具的心理测量学特性。240名围产期妇女(n = 155孕妇和n = 85产后)转介精神科会诊。在初步评估当天,所有女性都完成了GAD-7和爱丁堡产后抑郁量表(EPDS)。《精神疾病诊断与统计手册》第四版的诊断由经验丰富的精神科医生做出。将GAD-7和EPDS评分与临床诊断进行比较,以评估GAD-7和EPDS作为GAD筛查工具时的心理测量学特性。GAD-7在最佳临界值为13时的敏感性为61.3%,特异性为72.7%。与EPDS和EPDS-3A子量表相比,GAD-7在更大的截止评分范围内显示出更高的准确性和特异性,并且在合并MDD的患者中更准确地识别GAD。我们的研究结果表明,GAD-7代表了一个临床上有用的规模检测GAD在围产期妇女。
About 24.1% of pregnant women suffer from at least 1 anxiety disorder, 8.5% of whom suffer specifically from generalized anxiety disorder (GAD). GAD is often associated with major depressive disorder (MDD). During the perinatal period, the presence of physical and somatic symptoms often makes differentiation between depression and anxiety more challenging. To date, no screening tools have been developed to detect GAD in the perinatal population. We investigated the psychometric properties of the GAD 7-item Scale (GAD-7) as a screening tool for GAD in pregnant and postpartum women. Two hundred and forty perinatal women (n = 155 pregnant and n = 85 postpartum) referred for psychiatric consultation were enrolled. On the day of initial assessment, all women completed the GAD-7 and the Edinburgh Postnatal Depression Scale (EPDS). Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition–based diagnoses were made by experienced psychiatrists. Scores from the GAD-7 and EPDS were compared with the clinical diagnoses to evaluate the psychometric properties of the GAD-7 and EPDS when used as a screening tool for GAD. The GAD-7 yielded a sensitivity of 61.3% and specificity of 72.7% at an optimal cut-off score of 13. Compared with the EPDS and the EPDS-3A subscale, the GAD-7 displayed greater accuracy and specificity over a greater range of cut-off scores and more accurately identified GAD in patients with comorbid MDD. Our findings suggest that the GAD-7 represents a clinically useful scale for the detection of GAD in perinatal women.
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