Decreased functional connectivity in an executive control network is related to impaired executive function in Internet gaming disorder.
Decreased functional connectivity in an executive control network is related to impaired executive function in Internet gaming disorder.
复制标题
执行控制网络中功能连接的减少与网络游戏障碍中执行功能受损有关
DOI：
10.1016/j.pnpbp.2014.10.012
复制
发表时间：
2015-03-03
影响因子：
5.6
通讯作者：
Potenza, Marc N.
中科院分区：
文献类型：
--
作者：
Dong, Guangheng;Lin, Xiao;Potenza, Marc N.
关键词：
在精神病组中，跨皮质区域的静息大脑自发神经活动与特定的功能特性相关。互联网游戏障碍(IGD)患者表现出执行控制能力受损。因此，研究静息状态下的执行控制网络及其与任务执行过程中的执行控制之间的关系是非常重要的。35名IGD和36名健康对照组参与者接受了静息状态的fMRI扫描，并在MRI扫描仪内外执行了Stroop任务。计算Stroop效应与ECN感兴趣区(ROI)功能连接性之间的相关性。在安静状态下，IGD受试者的中枢神经系统的功能连通性低于HC受试者；中枢神经系统的功能连通性测量与Stroop效应负相关，与执行控制区的大脑激活呈正相关。在组内，IGD组和HC组ECNs的Stroop效应与功能连接性分别呈负趋势，IGD组和HC组的ECNs功能连接性与Stroop任务中的脑激活呈正趋势。中枢神经系统中更高的功能连接可能是更好的执行控制的基础，并可能提供对IGD的弹性。中枢神经系统功能连接性降低可能是认识和治疗IGD的一个重要特征。
Resting brain spontaneous neural activities across cortical regions have been correlated with specific functional properties in psychiatric groups. Individuals with Internet gaming disorder (IGD) demonstrate impaired executive control. Thus, it is important to examine executive control networks (ECNs) during resting states and their relationships to executive control during task performance. Thirty-five IGD and 36 healthy control participants underwent a resting-state fMRI scan and performed a Stroop task inside and outside of the MRI scanner. Correlations between Stroop effect and functional connectivity among ECN regions of interest (ROIs) were calculated within and between groups. IGD subjects show lower functional connectivity in ECNs than do HC participants during resting state; functional-connectivity measures in ECNs were negatively correlated with Stroop effect and positively correlated with brain activations in executive-control regions across groups. Within groups, negative trends were found between Stroop effect and functional connectivity in ECNs in IGD and HC groups, separately; positive trends were found between functional connectivity in ECNs and brain activations in Stroop task in IGD and HC groups, separately. Higher functional connectivity in ECNs may underlie better executive control and may provide resilience with respect to IGD. Lower functional connectivity in ECNs may represent an important feature in understanding and treating IGD.
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影响因子：
4.2
作者：
DeVito EE;Worhunsky PD;Carroll KM;Rounsaville BJ;Kober H;Potenza MN
通讯作者：
Potenza MN
网络游戏成瘾者静息态大脑活动区域同质性的变化
DOI：
10.1186/1744-9081-8-41
发表时间：
2012-08-18
期刊：
Behavioral and brain functions : BBF
影响因子：
--
作者：
Dong G;Huang J;Du X
通讯作者：
Du X
前兆或后遗症：网络成瘾者的病理障碍
影响因子：
3.7
作者：
Dong G;Lu Q;Zhou H;Zhao X
通讯作者：
Zhao X
DOI：
10.1016/j.pnpbp.2013.07.007
发表时间：
2013-10-01
影响因子：
5.6
作者：
Dong, Guangheng;Hu, Yanbo;Lin, Xiao
通讯作者：
Lin, Xiao
影响因子：
4.2
作者：
Franken, Ingmar H. A.;van Strien, Jan W.;Kuijpers, Ilse
通讯作者：
Kuijpers, Ilse