Moving from millifluidic to truly microfluidic sub-100-μm cross-section 3D printed devices.

Moving from millifluidic to truly microfluidic sub-100-μm cross-section 3D printed devices.
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DOI:
10.1007/s00216-017-0398-3
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发表时间:
2017-07
影响因子:
4.3
通讯作者:
Woolley AT
Woolley AT
中科院分区:
化学2区
文献类型:
--
作者:
Beauchamp MJ;Nordin GP;Woolley AT

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Three dimensional (3D) printing has generated considerable excitement in recent years regarding the extensive possibilities of this enabling technology. One area in which 3D printing has potential, not only for positive impact but also for substantial improvement, is microfluidics. To date many researchers have used 3D printers to make fluidic channels directed at point of care or lab on a chip applications. Here, we look critically at the cross-sectional sizes of these 3D printed fluidic structures, classifying them as millifluidic (>1 mm), sub-millifluidic (0.5–1.0 mm), large microfluidic (100–500 μm), or truly microfluidic (<100 μm). Additionally, we provide our prognosis for making 10–100 μm cross-section microfluidic features with custom formulated resins and stereolithographic printers. Such 3D printed microfluidic devices for bioanalysis will accelerate research through designs that can be easily created and modified, allowing improved assays to be developed.
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