Are insecticide-treated bednets more protective against Plasmodium falciparum than Plasmodium vivax-infected mosquitoes?
Are insecticide-treated bednets more protective against Plasmodium falciparum than Plasmodium vivax-infected mosquitoes?
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杀虫剂处理的床网是否比疟原虫感染的蚊子更具保护性对恶性疟原虫？
DOI：
10.1186/1475-2875-5-15
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发表时间：
2006-02-21
期刊：
影响因子：
3
通讯作者：
Dagoro H
中科院分区：
文献类型：
--
作者：
Bockarie MJ;Dagoro H
巴布亚新几内亚采用杀虫剂处理的蚊帐 (ITN) 控制疟疾的干预措施的结果往往表明对恶性疟原虫和间日疟原虫具有不同的保护作用。关于驱虫蚊帐对感染恶性疟原虫或间日疟原虫的蚊子相对丰度的影响知之甚少。本文描述了恶性疟原虫和间日疟原虫感染的蚊子的叮咬周期，以及驱虫蚊帐干预对感染这两种寄生虫的蚊子比例的影响。在巴布亚新几内亚的东塞皮克省 (ESP) 和新爱尔兰省 (NIP) 进行了昆虫学调查。使用整夜（18:00 - 06:00）着陆捕获和 CDC 光诱捕方法收集蚊子，并通过 ELISA 测定物种特异性疟疾子孢子率。子孢子阳性蚊子在三个四小时时段（18:00-22:00、22:00-02:00 和 02:00-06:00）的分布表明，在人们在蚊帐的保护下睡觉之前，感染间日疟原虫的蚊子的比例较高。在干预村，引入驱虫蚊帐之前收集的 308 只蚊子中，有 8 只（2.0%）恶性疟原虫阳性，4 只（1.0%）间日疟原虫阳性，寄生虫比例为 2:1。引入驱虫蚊帐后捕获的 908 只蚊子的子孢子率显示，恶性疟原虫显着下降 (0.7%)，间日疟原虫略有增加 (1.3%)，干预后寄生虫比率为 1:2。在未使用驱虫蚊帐的东塞皮克省，恶性疟原虫仍然是 12 个月蚊子收集和每月恶性疟原虫：P. falciparum 的优势物种。 vivax 配方从 8:1 到 1.2:1 不等。这些发现表明，在经过处理的蚊帐下睡觉的人在睡前在蚊帐的保护下可能比感染恶性疟原虫的蚊子更容易接触间日疟。感染不同疟疾寄生虫的蚊子叮咬行为的这种差异可能部分解释了恶性疟原虫的变化。引入 ITN 后的 vivax 配方。
The outcomes of insecticide-treated bednet (ITN) interventions for malaria control in Papua New Guinea tend to suggest a differential protective effect against Plasmodium falciparum and Plasmodium vivax. Little is known about the impact of ITNs on the relative abundance of mosquitoes infected with either P. falciparum or P. vivax. This paper describes the biting cycle of P. falciparum and P. vivax-infected mosquitoes and the impact of an ITN intervention on the proportion of mosquitoes infected with either parasite species. Entomological investigations were performed in East Sepik (ESP) and New Ireland Provinces (NIP) of PNG. Mosquitoes were collected using the all-night (18:00 - 06:00) landing catch and CDC light-trap methods and species specific malaria sporozoite rates were determined by ELISA. The distribution of sporozoite positive mosquitoes in three four-hour periods (18:00-22:00, 22:00-02:00 & 02:00-06:00) showed that a higher proportion of P. vivax-infected mosquitoes were biting before people retired to bed under the protection of bednets. In the intervention village, the 308 mosquitoes collected before ITNs were introduced included eight (2.0%) P. falciparum-positive and four (1.0%) P. vivax-positive specimens, giving a parasite ratio of 2:1. The sporozoite rate determined from 908 mosquitoes caught after ITNs were introduced showed a significant decrease for P. falciparum (0.7%) and a slight increase for P. vivax (1.3%), resulting in a post intervention parasite ratio of 1:2. In the East Sepik Province, where ITNs were not used, P. falciparum remained the dominant species in 12 monthly mosquito collections and monthly P. falciparum:P. vivax formula varied from 8:1 to 1.2:1. These findings suggest that people sleeping under treated bednets may be more exposed to P. vivax than P. falciparum-infected mosquitoes before going to sleep under the protection of bednets. This difference in the biting behaviour of mosquitoes infected with different malaria parasites may partly explain the change in the P. falciparum:P. vivax formula after the introduction of ITNs.
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DOI：
10.1016/s0035-9203(96)90465-4
发表时间：
1996-01-01
影响因子：
2.2
作者：
Bockarie, MJ;Alexander, N;Alpers, M
通讯作者：
Alpers, M
DOI：
10.4269/ajtmh.1988.39.135
发表时间：
1988-08-01
影响因子：
3.3
作者：
BURKOT, TR;GRAVES, PM;HEYWOOD, PF
通讯作者：
HEYWOOD, PF
影响因子：
1.9
作者：
Bockarie, MJ;Tavul, L;Kazura, JW
通讯作者：
Kazura, JW
DOI：
10.1016/0035-9203(90)90073-n
发表时间：
1990-11-01
影响因子：
2.2
作者：
BURKOT, TR;GARNER, P;SPARK, R
通讯作者：
SPARK, R
影响因子：
6.4
作者：
Cole-Tobian, JL;Cortés, A;King, CL
通讯作者：
King, CL