Mitochondrial DNA evolution in mice.
Mitochondrial DNA evolution in mice.
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小鼠线粒体 DNA 进化。
DOI：
10.1093/genetics/105.3.681
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发表时间：
1983
期刊：
影响因子：
3.3
通讯作者：
Wilson,AC
中科院分区：
文献类型：
--
作者：
Ferris,SD;Sage,RD;Prager,EM;Ritte,U;Wilson,AC
本研究扩展了小鼠线粒体DNA（mtDNA）多样性的知识，包括208只动物属于8个物种的亚属Mus。高度纯化的mtDNA从每个已进行高分辨率限制性内切酶图谱相对于一个小鼠mtDNA的已知序列。在检查的300个切割位点中的约200个处遇到归因于碱基取代的变异，并且长度突变位于置换环中或附近。该基因组中不同功能区的变异性从小到大依次为：核糖体RNA、转运RNA、已知蛋白、置换环和未鉴定的阅读框架。系统发育分析证实了Sage和马歇尔修订的小鼠分类的实用性，根据该分类，在以前被认为是一个物种的复合体中至少有四种啮齿类小鼠和三种原住民小鼠。这些物种中研究最彻底的是Mus arteriticus，西欧和地中海地区的家鼠，这是所有50种实验室菌株的线粒体来源，也是欧洲人在过去几百年中引入北美和南美的野生家鼠的代表。野生代表（M. musculus）和其他几种哺乳动物物种。相比之下，在许多已知或怀疑来源于宠物鼠贸易的实验室品系中，品系间几乎没有变异，大多数品系具有“古老的近交系”类型的家鼠mtDNA，其在145只野生小鼠中的频率很低，约为0.04。同样值得注意的是，固定了六条或更多融合染色体的家养小种的mtDNA具有明显的同质性，并且其中一些mtDNA与核型正常的小鼠的mtDNA有密切的关系。此外，本文还讨论了化石和其他证据，以证明小鼠和许多其他哺乳动物一样，线粒体DNA点突变分歧的平均速率为每百万年2-4%。由此，据估计，老鼠和我们的祖先之间的共生关系始于100多万年前，即，at a early早期stage阶段in the evolution进化ofHomo直立人erectus.
This study extends knowledge of mitochondrial DNA (mtDNA) diversity in mice to include 208 animals belonging to eight species in the subgenus Mus. Highly purified mtDNA from each has been subjected to high-resolution restriction mapping with respect to the known sequence of one mouse mtDNA. Variation attributed to base substitutions was encountered at about 200 of the 300 cleavage sites examined, and a length mutation was located in or near the displacement loop. The variability of different functional regions in this genome was as follows, from least to most: ribosomal RNA, transfer RNA, known proteins, displacement loop and unidentified reading frames.—Phylogenetic analysis confirmed the utility of the Sage and Marshall revision of mouse classification, according to which there are at least four species of commensal mice and three species of aboriginal mice in the complex that was formerly considered to be one species. The most thoroughly studied of these species isMus domesticus, the house mouse of Western Europe and the Mediterranean region, which is the mitochondrial source of all 50 of the laboratory strains examined and of the representatives of wild house mice introduced by Europeans to North and South America during the past few hundred years.—The level of mtDNA variation among wild representatives of (M. musculus) and several other mammalian species. By contrast, among the many laboratory strains that are known or suspected to stem from the pet mouse trade, there is little interstrain variation, most strains having the "old inbred" type ofdomesticusmtDNA, whose frequency in the 145 wild mice examined is low, about 0.04. Also notable is the apparent homogeneity of mtDNA indomesticusraces that have fixed six or more fused chromosomes and the close relationship of some of these mtDNAs to those of karyotypically normal mice.—In addition, this paper discusses fossil and other evidence for the view that in mice, as in many other mammals, the average rate of point mutational divergence in mtDNA is 2-4% per million years. From this, it is estimated that the commensal association between mice and our ancestors began more than a million years ago,i.e., at an early stage in the evolution ofHomo erectus.
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影响因子：
11.2
作者：
J. Staats
通讯作者：
J. Staats
猿线粒体 DNA 中存在广泛的多态性。
DOI：
--
发表时间：
1981
影响因子：
11.1
作者：
S. D. Ferris;Wesley M. BROWNt;William S. DAVIDSONt;Allan C. Wilson
通讯作者：
Allan C. Wilson
小鼠细胞表面抗原的细胞质遗传。
影响因子：
3.3
作者：
K. F. Lindahl;Barbara Hausmann
通讯作者：
Barbara Hausmann
基于线粒体DNA限制性内切酶切割模式的实验小鼠与家鼠亚种的关系
DOI：
10.1266/jjg.55.289
发表时间：
1980
期刊：
The Japanese Journal of Genetics
影响因子：
--
作者：
H. Yonekawa;K. Moriwaki;O. Gotoh;J. Watanabe;J. Hayashi;N. Miyashita;M. Petras;Y. Tagashira
通讯作者：
Y. Tagashira
缺乏母源性抗原的小鼠中异常类型的线粒体 DNA。
影响因子：
14.9
作者：
S. D. Ferris;U. Ritte;K. Lindahl;E. M. Prager;A. Wilson
通讯作者：
A. Wilson