Widespread divergence between incipient Anopheles gambiae species revealed by whole genome sequences.
Widespread divergence between incipient Anopheles gambiae species revealed by whole genome sequences.
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DOI：
10.1126/science.1195755
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发表时间：
2010-10-22
期刊：
影响因子：
--
通讯作者：
Besansky NJ
中科院分区：
文献类型：
--
作者：
Lawniczak MK;Emrich SJ;Holloway AK;Regier AP;Olson M;White B;Redmond S;Fulton L;Appelbaum E;Godfrey J;Farmer C;Chinwalla A;Yang SP;Minx P;Nelson J;Kyung K;Walenz BP;Garcia-Hernandez E;Aguiar M;Viswanathan LD;Rogers YH;Strausberg RL;Saski CA;Lawson D;Collins FH;Kafatos FC;Christophides GK;Clifton SW;Kirkness EF;Besansky NJ
非洲热带严格冈比亚按蚊（冈比亚按蚊）是疟疾的主要传播媒介，目前正在形成M和S分子形式的物种。尽管有相当程度的杂交，但这些形式在幼虫生态学和生殖行为上通过未知的遗传机制发生了分歧。先前使用基于基因的微阵列的全基因组扫描揭示了M和S之间的差异，这些差异主要局限于基因贫乏的中心点周围区域，从而促进了物种与持续基因流动的模型，该模型仅涉及着丝粒附近约3%的基因组在物种形成过程中。在这里，基于完整的M和S基因组序列，我们报告了广泛和异质的基因组差异，这与明显水平的形式间基因流动不一致，表明物种形成过程更先进，识别对启动该过程至关重要的基因面临更大的挑战。
The Afrotropical mosquito Anopheles gambiae sensu stricto (A. gambiae), a major vector of malaria, is currently undergoing speciation into the M and S molecular forms. These forms have diverged in larval ecology and reproductive behavior through unknown genetic mechanisms, despite considerable levels of hybridization. Previous genome-wide scans using gene-based microarrays uncovered divergence between M and S that was largely confined to gene-poor pericentromeric regions, prompting a speciation-with-ongoing-gene-flow model that implicated only ~3% of the genome near centromeres in the speciation process. Here, based on the complete M and S genome sequences, we report widespread and heterogeneous genomic divergence inconsistent with appreciable levels of inter-form gene flow, suggesting a more advanced speciation process and greater challenges to identify genes critical to initiating that process.
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影响因子：
3.8
作者：
della Torre, A;Tu, ZJ;Petrarca, V
通讯作者：
Petrarca, V
DOI：
10.1126/science.1193036
发表时间：
2010-10-22
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Neafsey DE;Lawniczak MKN;Park DJ;Redmond SN;Coulibaly MB;Traoré SF;Sagnon N;Costantini C;Johnson C;Wiegand RC;Collins FH;Lander ES;Wirth DF;Kafatos FC;Besansky NJ;Christophides GK;Muskavitch MAT
通讯作者：
Muskavitch MAT
影响因子：
3
作者：
Caputo B;Nwakanma D;Jawara M;Adiamoh M;Dia I;Konate L;Petrarca V;Conway DJ;della Torre A
通讯作者：
della Torre A
DOI：
10.1111/j.1558-5646.2008.00486.x
发表时间：
2008-12
期刊：
Evolution; international journal of organic evolution
影响因子：
--
作者：
Li YF;Costello JC;Holloway AK;Hahn MW
通讯作者：
Hahn MW
影响因子：
2.6
作者：
Du, W;Awolola, TS;Zheng, L
通讯作者：
Zheng, L