Human bocavirus infections in hospitalized children and adults.
Human bocavirus infections in hospitalized children and adults.
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DOI：
10.3201/eid1402.070851
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发表时间：
2008-02
影响因子：
11.8
通讯作者：
Boivin G
中科院分区：
文献类型：
--
作者：
Longtin J;Bastien M;Gilca R;Leblanc E;de Serres G;Bergeron MG;Boivin G
这种病毒在受感染儿童中的致病作用尚不清楚。研究报告了人类博卡病毒(HBoV)在患有呼吸道感染(RTI)的儿童中的感染，但仅偶尔在成人中感染。我们从2002-2003年冬季加拿大慢性支气管炎或肺炎加重的成人、因急性呼吸道感染住院的儿童和无症状儿童的鼻咽抽吸物(NPA)中搜索HBoV DNA。126名有症状成人中有1名(0.8%)、225名有症状儿童中有31名(13.8%)和100名接受择期手术的无症状儿童中有43名(43%)检出HBoV。在来自有症状儿童的31例HBoV阳性NPA中，有22例(71%)检测到另一种病毒。鉴定出HBoV的两个分支。HBoV在呼吸道感染中的致病作用尚不确定，因为它经常在有症状和无症状的儿童中检测到，并通常与其他病毒一起在有症状的儿童中发现。
The pathogenic role of this virus in infected children is unclear. Studies have reported human bocavirus (HBoV) in children with respiratory tract infections (RTIs), but only occasionally in adults. We searched for HBoV DNA in nasopharyngeal aspirates (NPAs) from adults with exacerbations of chronic bronchitis or pneumonia, from children hospitalized for acute RTIs, and from asymptomatic children during the winter of 2002–2003 in Canada. HBoV was detected in NPAs of 1 (0.8%) of 126 symptomatic adults, 31 (13.8%) of 225 symptomatic children, and 43 (43%) of 100 asymptomatic children undergoing elective surgery. Another virus was detected in 22 (71%) of the 31 HBoV-positive NPAs from symptomatic children. Two clades of HBoV were identified. The pathogenic role of HBoV in RTIs is uncertain because it was frequently detected in symptomatic and asymptomatic children and was commonly found with other viruses in symptomatic children.
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影响因子：
3.7
作者：
Weissbrich, Benedikt;Neske, Florian;Kreth, Hans Wolfgang
通讯作者：
Kreth, Hans Wolfgang
DOI：
10.1073/pnas.0504666102
发表时间：
2005-09-06
影响因子：
11.1
作者：
Allander, T;Tammi, MT;Andersson, B
通讯作者：
Andersson, B
影响因子：
6.4
作者：
Fry, Alicia M.;Lu, Xiaoyan;Olsen, Sonja J.
通讯作者：
Olsen, Sonja J.
影响因子：
11.8
作者：
Chung, Ju-Young;Han, Tae Hee;Kim, Sang Woo
通讯作者：
Kim, Sang Woo
影响因子：
9.4
作者：
Kleines, Michael;Scheithauer, Simone;Haeusler, Martin
通讯作者：
Haeusler, Martin