Developing Diagnostic and Therapeutic Approaches to Bacterial Infections for a New Era: Implications of Globalization.
Developing Diagnostic and Therapeutic Approaches to Bacterial Infections for a New Era: Implications of Globalization.
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DOI：
10.3390/antibiotics9120916
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发表时间：
2020-12-16
期刊：
影响因子：
--
通讯作者：
García-Suárez MDM
中科院分区：
文献类型：
--
作者：
Fernández L;Cima-Cabal MD;Duarte AC;Rodriguez A;García P;García-Suárez MDM
在短短几个月的时间里，当前的冠状病毒大流行暴露了对人类健康采取更全球化方法的必要性。事实上，传染病的迅速蔓延及其在人命和经济损失方面不可预测的后果，将要求我们在临床和研究两方面改变战略。最终，我们应该准备好与影响世界不同地区大量人口的传染病作斗争。这种新情况将需要快速、廉价的诊断系统，适用于世界任何地方，最好不需要专门人员。此外，这些疾病的治疗必须是通用的、易于扩展的、便宜的和易于应用的。所有这一切只有在各国政府的共同支持下才有可能实现，各国政府将不得不使批准新疗法的要求更加灵活。与此同时，制药部门必须承诺优先考虑全球利益的产品，而不是最有利可图的产品。极端的情况需要激烈的反应，任何利润损失都可能在未来带来好处。在这里，我们总结了发展中的技术注定要面对传染病带来的当前和未来的健康挑战，并讨论了哪些技术更有可能被实施。
In just a few months, the current coronavirus pandemic has exposed the need for a more global approach to human health. Indeed, the quick spread of infectious diseases and their unpredictable consequences, in terms of human lives and economic losses, will require a change in our strategy, both at the clinical and the research level. Ultimately, we should be ready to fight against infectious diseases affecting a huge number of people in different parts of the world. This new scenario will require rapid, inexpensive diagnostic systems, applicable anywhere in the world and, preferably, without the need for specialized personnel. Also, treatments for these diseases must be versatile, easily scalable, cheap, and easy to apply. All this will only be possible with joint support of the governments, which will have to make the requirements for the approval of new therapies more flexible. Meanwhile, the pharmaceutical sector must commit to prioritizing products of global interest over the most profitable ones. Extreme circumstances demand a vehement response, and any profit losses may well pay dividends going forward. Here, we summarize the developing technologies destined to face the current and future health challenges derived from infectious diseases and discuss which ones have more possibilities of being implemented.
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DOI：
10.3390/v10060335
发表时间：
2018-06-19
期刊：
Viruses
影响因子：
--
作者：
Hatoum-Aslan A
通讯作者：
Hatoum-Aslan A
影响因子：
5.7
作者：
Cheng, Yu-Shan;Sun, Wei;Zheng, Wei
通讯作者：
Zheng, Wei
影响因子：
9.4
作者：
Chowdhury, Imran Hussain;Sen, Aditi;Bhattacharya, Basudev
通讯作者：
Bhattacharya, Basudev
DOI：
10.1007/978-1-60327-999-4_7
发表时间：
2009-01-01
期刊：
MOLECULAR EPIDEMIOLOGY OF MICROORGANISMS
影响因子：
--
作者：
Ecker, David J.;Massire, Christian;Sampath, Rangarajan
通讯作者：
Sampath, Rangarajan
影响因子：
30.3
作者：
Hsu, Bryan B.;Gibson, Travis E.;Gerber, Georg K.
通讯作者：
Gerber, Georg K.