Modular polymer-caged nanobins as a theranostic platform with enhanced magnetic resonance relaxivity and pH-responsive drug release.
Modular polymer-caged nanobins as a theranostic platform with enhanced magnetic resonance relaxivity and pH-responsive drug release.
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DOI:
10.1002/anie.201004867
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发表时间:
2010-12-17
影响因子:
16.6
通讯作者:
Nguyen, SonBinh T.
中科院分区:
文献类型:
--
作者:
Lee, Sang-Min;Song, Ying;Hong, Bong Jin;MacRenaris, Keith W.;Mastarone, Daniel J.;O'Halloran, Thomas V.;Meade, Thomas J.;Nguyen, SonBinh T.
‘Clickable’ polymer-caged nanobins enable the combination of GdIII MRI contrast agents and an anticancer drug (gemcitabine, GMC) into a single theranostic platform. The resulting GdIII-conjugated, GMC-loaded PCNs (GdIII-PCNGMC) exhibit significant enhancements in r1 relaxivity, drug uptake, and pH-sensitive drug release.
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影响因子:
3
作者:
Moog, R;Burger, AM;Massing, U
通讯作者:
Massing, U
影响因子:
--
作者:
Allen, MJ;MacRenaris, KW;Meade, TJ
通讯作者:
Meade, TJ
影响因子:
15
作者:
Frias, JC;Williams, KJ;Fayad, ZA
通讯作者:
Fayad, ZA
影响因子:
10.8
作者:
Maeda, H;Wu, J;Hori, K
通讯作者:
Hori, K
DOI:
10.1073/pnas.76.1.145
发表时间:
1979-01-01
影响因子:
11.1
作者:
ENOCH, HG;STRITTMATTER, P
通讯作者:
STRITTMATTER, P