Factors associated with health-related quality of life in a cohort of cancer survivors in New Jersey.
Factors associated with health-related quality of life in a cohort of cancer survivors in New Jersey.
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DOI：
10.1186/s12885-023-11098-5
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发表时间：
2023-07-14
期刊：
影响因子：
3.8
通讯作者：
Evens, Andrew M.
中科院分区：
文献类型：
--
作者：
Manne, Sharon;Devine, Katie;Hudson, Shawna;Kashy, Deborah;O'Malley, Denalee;Paddock, Lisa E.;Bandera, Elisa V.;Llanos, Adana A. M.;Fong, Angela;Singh, Neetu;Frederick, Sara;Evens, Andrew M.
虽然有大量文献研究与癌症幸存者健康相关的生活质量（HRQoL）相关，但很少有人关注社会经济劣势和幸存者护理过渡经历在HRQoL中的作用。很少有大型队列研究包括一套全面的相关因素，以获得与幸存者HRQ0L相关的全貌。本队列研究旨在探讨健康的社会决定因素、健康史、健康行为、幸存者护理经历和HRQoL的社会心理因素之间的关系。符合条件的幸存者是被诊断患有泌尿生殖系统癌、女性乳腺癌、妇科癌、结肠直肠癌、肺癌、黑色素瘤或甲状腺癌的新泽西州居民。参与者完成了社会决定因素、健康行为、幸存者护理经历、心理社会因素和HRQoL的测量。对五个领域（社会决定因素、健康史、健康行为、幸存者护理经历、心理社会因素）分别建立预测HRQoL的多元回归模型。获得统计显著性的变量被包括在按五个域排列的分层多元回归中。864名癌症幸存者完成了这项调查。较低的总体HRQoL与失业、更多合并症、较不健康的饮食、较低的生存准备、更多未满足的支持需求以及对癌症复发的较高恐惧相关。两个社会心理因素，未满足的支持需求和害怕复发，在HRQoL中起着最重要的作用，占方差的20%以上。未满足的支持需求和对复发的恐惧与身体、功能和情感HRQoL域有显著相关性。旨在改善癌症幸存者HRQoL的干预措施可能受益于改善合并症医疗问题的协调管理，促进更健康的饮食，解决未满足的支持需求，并减少幸存者对癌症复发的恐惧。在线版本包含补充材料，可在10.1186/s12885-023-11098-5获得。
Although there is extensive literature on correlates of health-related quality of life (HRQoL) among cancer survivors, there has been less attention paid to the role of socioeconomic disadvantage and survivorship care transition experiences in HRQoL. There are few large cohort studies that include a comprehensive set of correlates to obtain a full picture of what is associated with survivors’ HRQ0L. This cohort study of recent cancer survivors in New Jersey aimed to explore the association between social determinants of health, health history, health behaviors, survivorship care experiences, and psychosocial factors in HRQoL. Eligible survivors were residents of New Jersey diagnosed with genitourinary, female breast, gynecologic, colorectal, lung, melanoma, or thyroid cancers. Participants completed measures of social determinants, health behaviors, survivorship care experiences, psychosocial factors, and HRQoL. Separate multiple regression models predicting HRQoL were conducted for each of the five domains (social determinants, health history, health behaviors, survivorship care experiences, psychosocial factors). Variables attaining statistical significance were included in a hierarchical multiple regression arranged by the five domains. 864 cancer survivors completed the survey. Lower global HRQoL was associated with being unemployed, more comorbidities, a less healthy diet, lower preparedness for survivorship, more unmet support needs, and higher fear about cancer recurrence. Two psychosocial factors, unmet support needs and fear of recurrence, played the most important role in HRQoL, accounting for more than 20% of the variance. Both unmet support needs and fear of recurrence were significant correlates of physical, functional, and emotional HRQoL domains. Interventions seeking to improve cancer survivors’ HRQoL may benefit from improving coordinated management of comorbid medical problems, fostering a healthier diet, addressing unmet support needs, and reducing survivors’ fears about cancer recurrence. The online version contains supplementary material available at 10.1186/s12885-023-11098-5.
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